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18 results on '"Helen B Pearson"'

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1. The PTEN conundrum: how to target PTEN-deficient prostate cancer

2. The Dual Inhibition of RNA Pol I Transcription and PIM Kinase as a New Therapeutic Approach to Treat Advanced Prostate Cancer

3. Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution

4. Myb via TGFβis required for collagen type 1 production and skin integrity

5. Identification of

6. Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo

7. Increasing Intracellular Bioavailable Copper Selectively Targets Prostate Cancer Cells

8. A Chemical Screening Approach to Identify Novel Key Mediators of Erythroid Enucleation

9. The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis

10. Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

11. Keratin 76 is required for tight junction function and maintenance of the skin barrier

12. Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration

13. Dissecting the role of polarity regulators in cancer through the use of mouse models

14. Scribble Modulates the MAPK/Fra1 Pathway to Disrupt Luminal and Ductal Integrity and Suppress Tumour Formation in the Mammary Gland

15. Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo

16. SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

17. K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse

18. Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine

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