1. Diagnostic exercise: ascites, abdominal masses, and diffuse peritoneal nodules in a rat.
- Author
-
Cooper TK, Dumpala PR, and Whitcomb TL
- Subjects
- Animals, Ascites pathology, Ascites veterinary, Cytological Techniques veterinary, Diagnosis, Differential, Dyspnea pathology, Dyspnea veterinary, Endodermal Sinus Tumor diagnosis, Endodermal Sinus Tumor pathology, Fatal Outcome, Female, Ovarian Neoplasms diagnosis, Ovarian Neoplasms pathology, Rats, Viscera pathology, Animals, Laboratory, Endodermal Sinus Tumor veterinary, Ovarian Neoplasms veterinary, Rodent Diseases diagnosis, Rodent Diseases pathology
- Abstract
A 1.4-year-old virgin female brown-hooded fancy rat presented for abdominal distention, jaundice, and dyspnea. At physical examination, a firm mass was palpable in the caudoventral abdomen as well as multiple small nodular masses associated with the abdominal viscera. At necropsy, in addition to a large mass replacing the left ovary and myriad nodules studding the peritoneal surface, there was 31 ml of abdominal effusion. By cytology, the abdominal fluid contained numerous pleomorphic vacuolated tumor cells surrounding globular pale eosinophilic to amphophilic acellular material that was strongly periodic acid-Schiff positive. Histologically, the tumor was biphasic with abundant acellular hyaline matrix that was also periodic acid-Schiff positive.
- Published
- 2014
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