5 results on '"Meijboom, Franck L. B."'
Search Results
2. Simulation of dual-purpose chicken breeding programs implementing gene editing.
- Author
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Chuang, Edward Y. S., Wellmann, Robin, Meijboom, Franck L. B., Tetens, Jens, and Bennewitz, Jörn
- Subjects
GENOME editing ,CHICKEN breeds ,ANIMAL welfare ,LOCUS (Genetics) ,GENETIC correlations ,SINGLE nucleotide polymorphisms ,CHICKS ,POULTRY breeding ,ANIMAL breeding - Abstract
Background: In spite of being controversial and raising ethical concerns, the application of gene editing is more likely to be accepted when it contributes to improving animal welfare. One of the animal welfare and ethical issues in chicken breeding is chick culling, the killing of the male layer chicks after hatching due to the poor fattening performance. Although establishing dual-purpose chicken lines could solve this problem, unfavorable genetic correlations between egg and meat production traits hindered their competitiveness. Although it is also controversial in ethical terms, gene editing may accelerate genetic progress in dual-purpose chicken and alleviate the ethical concerns from chick culling. Results: The simulation compared the utility improvement in dual-purpose use under two breeding schemes: one consisting in the improvement of the laying hens, and the second in the improvement of a synthetic line obtained from a layer broiler cross. In each breeding scheme, the breeding programs were simulated with and without gene editing. Polygenic breeding values and 500 simulated quantitative trait loci (QTL) with different levels of pleiotropy caused negative correlations between egg production, meat production, and overall health. The results of the simulation demonstrated that genetic gain could be accelerated by at most 81% for several generations if gene editing was used. The actual increase in genetic gain depended on the number of single nucleotide polymorphisms (SNPs) being edited per animal. The rate of genetic improvement became equal in scenarios with and without gene editing after 20 generations. This is because the remaining segregating QTL had small effects and their edition would have negative overall health effects from potential off-target edits. Although gene editing can improve genetic gain in quantitative traits, it can only be recommended as long as QTL with reasonable effect sizes are segregating and detectable. Conclusions: This simulation demonstrates the potential of gene editing to accelerate the simultaneous improvement of negatively correlated traits. When the risk of negative consequences from gene editing persists, the number of SNPs to be edited should be chosen carefully to obtain the optimal genetic gain. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
3. The development of animal welfare science in China: An explorative analysis.
- Author
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Xin Guo and Meijboom, Franck L. B.
- Subjects
ANIMAL development ,ANIMAL welfare ,ANIMAL science ,ANIMAL species ,ACADEMIC debating ,LABORATORY animals - Abstract
This paper presents results of a search and analysis of research projects on animal welfare registered in the China National Knowledge Infrastructure (CNKI) database in the period 1996-2019, with the aim of gaining a better understanding of developments in animal welfare science in China. The title-abstract search of publications in this database resulted in over 260 articles that could be linked to 200 research projects with an animal welfare component. These projects were analysed for: (a) involved academic disciplines; (b) studied animal species; (c) contexts of animal use; (d) concepts of animal welfare; and (e) attention to ethical dimensions of animal welfare. The analysis shows an increased attention to animal welfare science, with a particular focus on farm and laboratory animals. We observed an increase in the number of studies and of animal species studied. The majority of research projects start in or include a view of animal welfare that is close to Fraser's 'biological function' view. We conclude that the increased attention to animal welfare in science reflects recent developments in China in terms of public concern about animal use, academic debate about the importance of animal welfare, and animalrelated political and economic developments linked to China's ambitions to be a global player in science and food production. For the further development of animal welfare science in China stable funding and more interdisciplinary collaboration are necessary to study and publish on fundamental aspects of animal welfare, on issues not directly related to applied problems, and on the ethical dimensions of animal welfare. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
4. Attitudes of clients of Dutch pest controllers towards animal welfare in the management of liminal rodents.
- Author
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van Gerwen, Maite A. A. M., Rodenburg, T. Bas, Arndt, Saskia S., Meerburg, Bastiaan G., and Meijboom, Franck L. B.
- Subjects
ANIMAL welfare ,RODENTS ,RODENT control ,PESTS ,AGRICULTURE ,MICE - Abstract
Rodent control tends to involve methods that cause animal suffering, but little attention has been paid to the animal welfare implications of rodent control. The aim of the current study was to gain insight into the opinions and attitudes of clients of Dutch pest controllers, regarding liminal rodents, rodent control, and rodent welfare. A better understanding of their attitudes may contribute to more ethical rodent management programmes. An online survey among 248 clients of Dutch pest controllers was carried out. Respondents, especially those within the agricultural sector, have a relatively negative attitude towards rats and mice. Respondents in the agricultural subgroup do not consider the welfare of liminal rodents important. They also think that the welfare impact of commonly used control methods is limited, and they have low tolerance levels for the presence of rodents. Respondents from other sectors have a far more positive attitude towards rats and mice, consider their welfare to be of greater importance, have a greater estimation of the welfare impact of control methods and show greater tolerance levels towards rodents. The respondents from the latter subgroup have a similar attitude compared to Dutch pest controllers participating in a previous survey. The findings of the current study firstly provide useful information for the further development and practical implementation of preventive control methods. Secondly, they provide input for a more animal-friendly rodent control and for the development of an assessment framework to support ethical decisionmaking. Finally, they can be helpful for further research and the communication and co-operation between professional pest controllers and their clients. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
5. Farming ethics in practice: from freedom to professional moral autonomy for farmers
- Author
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Meijboom, Franck L B, Stafleu, Frans R., LS Wijsgerige Ethiek, OFR - Ethics Institute, LS Wijsgerige Ethiek, and OFR - Ethics Institute
- Subjects
Economic growth ,media_common.quotation_subject ,Public debate ,0211 other engineering and technologies ,02 engineering and technology ,Animal welfare ,Relevance (law) ,Quality (business) ,Sociology ,Autonomy ,media_common ,Farmers ,business.industry ,0402 animal and dairy science ,021107 urban & regional planning ,04 agricultural and veterinary sciences ,Public relations ,040201 dairy & animal science ,Consumer Organizations ,Professional ethics ,Agriculture ,business ,Agronomy and Crop Science - Abstract
Food production, water management, land use, and animal and public health are all topics of extensive public debate. These themes are linked to the core activities of the agricultural sector, and more specifically to the work of farmers. Nonetheless, the ethical discussions are mostly initiated by interest groups in society rather than by farmers. At least in Europe, consumer organizations and animal welfare and environmental organizations are more present in the public debate than farmers. This is not how it should be. First, because consumers often cannot but rely on agriculture. Second, because recent research shows that farmers have moral beliefs and convictions that appear to be broader than economic considerations and that are—to a certain extent—specific to their profession. This raises the question how to make input from farmers operational in the public debates on the future of farming. We discuss one option: entrusting farmers with professional autonomy concerning moral matters related to farming. We sketch the historical background of the current situation in which farmers are relatively silent on moral matters and we present some clear indications that farmers have values and moral beliefs that are relevant for the public debate. Next the concepts of professionalism and professional autonomy are discussed and applied to the practice of farming. Finally, we discuss the relevance and limits of professional moral autonomy for the agricultural profession. We close with an overview of what this moral autonomy implies for and requires from farmers in practice. We conclude that if some preconditions are met by farmers, then this type of moral autonomy can be relevant for farmers and for society, and contributes to the quality of the public debate on the future of farming.
- Published
- 2015
- Full Text
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