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This work presents a generalized angle-dependent ray transfer function that can accurately map the angular and spatial distribution of light intensities on the tissue surface onto a camera image plane in a non-contact camera-based imaging system. The method developed here goes beyond existing ray transfer models that apply to angle-averaged tomographic data alone. The angle-dependent ray transfer operator was constructed using backward ray tracing based on radiation surface theory. The proposed method was validated using numerical phantoms and experimental data from an actual non-contact imaging system. [ABSTRACT FROM AUTHOR]