1. Prinzmetal's variant angina: hemodynamic and angiographic observations during pain.
- Author
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Gaasch WH, Adyanthaya AV, Wang VH, Pickering E, Quinones MA, and Alexander JK
- Subjects
- Adult, Angina Pectoris diagnostic imaging, Angina Pectoris drug therapy, Angiocardiography, Blood Pressure, Cardiac Catheterization, Cardiac Output, Cineangiography, Coronary Angiography, Coronary Artery Bypass, Female, Heart Conduction System physiopathology, Heart Rate, Humans, Male, Middle Aged, Myocardium metabolism, Nitroglycerin therapeutic use, Oxygen Consumption, Saphenous Vein, Angina Pectoris physiopathology, Coronary Circulation, Hemodynamics
- Abstract
Hemodynamic and angiographic data obtained during pain from four patients with Prinzmetal's variant angina are reported. The left ventricular pressure-time index did not increase before or during attacks of angina in three of the four patients; left ventricular systolic performance was impaired during pain in all three. In one of these three patients left ventricular pressure-volume data obtained during angina suggested a reduction in diastolic compliance; in another, pain and S-T segment elevation were present during coronary arterial spasm. The fourth patient had an increase in both arterial blood pressure and heart rate before an attack; in this patient coronary arterial spasm could not be demonstrated during the period of pain and S-T elevation. The data presented suggest that hemodynamic factors that increase the myocardial oxygen requirements are absent and that coronary arterial spasm is present in some, but not all, patients with variant angina.
- Published
- 1975
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