Search

Background Internal carotid artery (ICA) occlusion associated with posterior cerebral artery (PCA) aneurysms is regarded as a rare cerebrovascular disease. Common treatment of aneurysms—direct clipping or coiling—is not taken into consideration for this kind of cerebrovascular property. Combined surgical cerebrovascular reconstruction of the superficial temporal artery−to−middle cerebral artery (STA-MCA) bypass offers a chance to downregulate the hemodynamic stress of aneurysm rupture. Case Description A 46-year-old female presented with a fever and headache 1 month ago. An axial computed tomography scan showed a subarachnoid hemorrhage (SAH). Digital subtraction angiography (DSA) was conducted, and the patient received an STA-MCA bypass following medical treatment for 1 month in the local hospital. Computed tomography angiography and DSA demonstrated an aneurysm located on the right PCA and an occlusion of the right ICA in our hospital. Three days after admission, the right STA-MCA bypass was performed. The patient suffered no neurologic deterioration and lived a normal life. 6 months after the STA-MCA bypass, DSA of the right vertebral artery revealed disappearance of the aneurysm located on the right PCA (P2 segment). Conclusions Owing to ICA occlusion, the gap of hemodynamic stress between the posterior segment of the circle of Willis and anterior segment of the circle of Willis enlarged. This may lead to a ruptured PCA aneurysm. In this case, the aneurysm disappeared following an STA-MCA bypass. STA-MCA bypass may be one of the major reasons downregulating the gap, which can be regarded as an effective option concerning such aneurysms. [ABSTRACT FROM AUTHOR]

Complex middle cerebral artery (MCA) aneurysms, including aneurysms that are sizeable (large or giant), fusiform, wide-necked or calcified, remain a significant challenge during microsurgical clipping or endovascular coiling as treatment strategies. In the present study, a retrospective analysis of cases of this type of aneurysm treated between August 2012 and December 2019 was performed. From the hospital's database, a total of 13 patients (7 males and 6 females) with a mean age of 39.0 years (range, 13-65 years) were identified. The mean size of the aneurysms was 17.5 mm (range, 3.9-35.0 mm). A total of four patients (30.8%) had ruptured aneurysms and nine (69.2%) had unruptured aneurysms. All aneurysms were treated by proximal occlusion of the parent artery, trapping or excision combined with cerebral revascularization. The bypasses performed included 10 extracranial-intracranial bypasses and 3 intracranial-intracranial bypasses (1 end-to-end re-anastomosis, 1 interpositional graft and 1 end-to-side reimplantation). Postoperative angiography confirmed that the bypass patency was 92.3% and the clinical outcomes were indicated to be favorable, with a modified Rankin Scale score ≤2 in 12 out of 13 patients (92.3%) at the last follow-up. Taken together, the results of the present analysis suggested that treatment strategies for complex MCA aneurysms should depend on the status and characteristics of the aneurysm, including aneurysm size, location and morphology. For aneurysms that lack perforating arteries in the aneurysm dome, clip trapping or aneurysm excision with or without bypass are preferred as treatment strategies. When there are perforating arteries (particularly the lenticulostriate artery) arising from the aneurysm dome, however, the aneurysms should be treated with bypass followed by proximal occlusion of the parent artery or clip reconstruction. [ABSTRACT FROM AUTHOR]

Very small intracranial aneurysms (VSIAs) are challenging to treat because aneurysm tearing and clip slippage can occur during neurosurgical clipping. In this study, we introduce and share our experience with cotton-assisted clipping of VSIAs. We retrospectively analyzed the data of 20 patients with 24 VSIAs treated with cotton-assisted clipping between February 2008 and December 2014 in the Neurosurgery Departments of the First Affiliated Hospital, Soochow University and Taizhou People's Hospital. During surgery, 2 aneurysm necks were torn. To treat the tears, we wrapped rectangular cotton pads around the parental arteries at the site of rupture. The remaining 22 aneurysms were clipped after being wrapped in cotton pads. The 2 aneurysm ruptures were successfully repaired with cotton-assisted clipping. In the remaining 22 aneurysms, no cases of aneurysm clip slippage or aneurysm rupture occurred. Patients were followed up on average for 59.0 months (range, 30–113 months). Of the 20 patients, the 16 patients with preoperative Hunt–Hess grades of 1–3 recovered well after the surgery (Glasgow Outcome Scale [GOS] score, 5). Of the 4 patients with Hunt–Hess grades of 4–5, 3 had a good recovery (GOS scores, 4–5), and 1 patient died of heart disease 6 months after being discharged from the hospital; this patient had a GOS score of 4 at the time of discharge. Cotton-assisted clipping could prevent aneurysm clip slipping and aneurysm rupture and facilitate the repair of aneurysm neck tears. This technique is a useful alternative therapy for VSIAs. [ABSTRACT FROM AUTHOR]