1. Suppression of hemoglobin H in disorders of iron metabolism.
- Author
-
Saleem A, Irani DR, Bart JB, and Alfrey CP Jr
- Subjects
- Adolescent, Adult, Alcohol Drinking, Anemia, Hypochromic diagnosis, Anemia, Sideroblastic diagnosis, Chronic Disease, Female, Hemoglobin H analysis, Humans, Iron metabolism, Iron Deficiencies, Anemia, Hypochromic blood, Anemia, Sideroblastic blood, Hemoglobin H metabolism, Hemoglobins, Abnormal metabolism
- Abstract
Disorders of iron metabolism affect the expression of hemoglobin H in hemoglobin H disease. Two cases of iron deficiency with reduced synthesis of hemoglobin H are described in the literature. We report two more cases, one with anemia of chronic disease and another with alcoholic sideroblastic anemia where the hemoglobin H was not detected at presentation and appeared after treatment of the underlying disorder. The pathogenesis of suppression of hemoglobin H is discussed.
- Published
- 1987
- Full Text
- View/download PDF