1. Antioxidant and androgenic effects of dietary ginger on reproductive function of male diabetic rats.
- Author
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Ghlissi Z, Atheymen R, Boujbiha MA, Sahnoun Z, Makni Ayedi F, Zeghal K, El Feki A, and Hakim A
- Subjects
- Androgens therapeutic use, Animals, Antioxidants metabolism, Antioxidants therapeutic use, Catalase metabolism, Diabetes Complications enzymology, Diabetes Complications metabolism, Glutathione Peroxidase metabolism, Infertility metabolism, Lipid Peroxidation drug effects, Male, Malondialdehyde metabolism, Phytotherapy, Plant Preparations pharmacology, Plant Preparations therapeutic use, Rats, Rats, Wistar, Rhizome, Semen drug effects, Superoxide Dismutase metabolism, Testis metabolism, Testosterone blood, Androgens pharmacology, Antioxidants pharmacology, Diabetes Complications prevention & control, Diet, Zingiber officinale, Infertility prevention & control, Oxidative Stress drug effects
- Abstract
This study evaluated the antioxidant and androgenic properties of ginger roots on the reproductive function of male diabetic rats. Animals were divided into three groups; the control (Control), diabetic (Diab) and diabetic fed with dietary ginger for 30 d (Diab + Z). Thereafter, blood samples were collected and reproductive organs (testis, epididymis, prostate and seminal vesicle) were removed for determination of sperm parameters, malondialdehyde (MDA) level, glutathione peroxidase (GPx), superoxide dismutase (SOD), catalase (CAT), lactate dehydrogenase (LDH), alkaline phosphatase (ALP) and aspartate and lactate aminotransferase (AST and ALT) activities. Dietary ginger decreased blood glucose and MDA level, increased reproductive organ weights and testosterone level, improved semen quantity and motility, and ameliorated the SOD, CAT and GPx activities as well as testis AST, ALT, LDH and ALP activities. Intake of ginger roots improves the antioxidant and androgenic reproductive function of male diabetic rats in addition to its antidiabetic property.
- Published
- 2013
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