1. Azoospermia due to testicular amyloidosis in a patient with familial Mediterranean fever.
- Author
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Haimov-Kochman R, Prus D, and Ben-Chetrit E
- Subjects
- Amyloid analysis, Amyloidosis pathology, Aortic Valve, Aortic Valve Stenosis complications, Aortic Valve Stenosis surgery, Biopsy, Familial Mediterranean Fever pathology, Humans, Kidney Diseases complications, Kidney Diseases surgery, Kidney Failure, Chronic etiology, Kidney Failure, Chronic surgery, Male, Middle Aged, Oligospermia pathology, Spermatogenesis, Testicular Diseases pathology, Testis chemistry, Testis pathology, Amyloidosis complications, Familial Mediterranean Fever complications, Oligospermia etiology, Testicular Diseases complications
- Abstract
We describe a patient suffering from familial Mediterranean fever (FMF) who presented to our clinic with secondary infertility of 2 years due to amyloid A amyloidosis. His spermiogram disclosed azoospermia. A testicular biopsy revealed hyalinized tubules devoid of full spermatogenesis and containing abundant amyloid, confirmed by Congo red stain. We suggest that testicular amyloidosis be taken into consideration when dealing with azoospermic FMF patients. In view of the progressive nature of amyloid accumulation in the testis we propose to follow routinely the spermiogram of FMF patients with renal amyloidosis. Furthermore, consideration of sperm cryopreservation is suggested in these cases. In FMF patients with azoospermia consideration of testicular biopsy is recommended as early as possible in order to increase the chance of sperm retrieval.
- Published
- 2001
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