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1. [Study of components of standard samples of polyene macrolide antibiotics by the methods of high performance liquid chromatography and SIEAP mass spectrometry].

Author

Mitrofanova VG, Mirgorodskaia OA, Derzhavets AA, Matveeva ER, Shenin IuD, and Morgunova AF

Subjects
Amphotericin B standards, Anti-Bacterial Agents standards, Candicidin standards, Chromatography, High Pressure Liquid methods, Mass Spectrometry methods, Molecular Weight, Nystatin standards, Polyenes analysis, Polyenes standards, Reference Standards, World Health Organization, Amphotericin B analysis, Anti-Bacterial Agents analysis, Candicidin analysis, Nystatin analysis
Abstract

The component composition of reference samples of polyenic macrolide antibiotics such as nystatin, mycoheptin, amphotericin B and levorin was studied by HPLC and chromatographic mass spectrometry in comparison to the WHO standards. It was shown that the samples were close by their component composition to the analogous samples of the WHO standards.

Published
1991

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