1. Aripiprazole causing false positive urine amphetamine drug screen in an adult patient with bipolar disorder.
- Author
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Caricasole V, Spagnolo G, Di Bernardo I, Cirnigliaro G, Piccoli E, and Dell'Osso B
- Subjects
- Adult, Antipsychotic Agents therapeutic use, Aripiprazole therapeutic use, Bipolar Disorder drug therapy, False Positive Reactions, Female, Humans, Amphetamines urine, Antipsychotic Agents urine, Aripiprazole urine, Bipolar Disorder urine, Substance Abuse Detection statistics & numerical data
- Abstract
There has been only a few reports regarding aripiprazole causing false positive urine amphetamine drug screens, exclusively on children accidently ingesting aripiprazole. Herein, we present the first reported case of a 40 year old woman affected by Bipolar I Disorder, treated with aripirazole at therapeutic oral dose ranging from 15 mg/day to 30 mg/day, in the context of a depressive episode with mixed and psychotic features, showing a false positive urine amphetamine drug screen. We document the relationship between aripiprazole-dose, plasma concentration and amphetamines values in toxicologic urine examinations over time. Awareness of potential false positive urine amphetamine drug screens during aripiprazole treatment can condition therapeutic choices and prevent legal implications., (Copyright © 2019. Published by Elsevier Inc.)
- Published
- 2019
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