1. [Detection of myocardial lesion in patients with acute ammonia poisoning].
- Author
-
Zhang YX, Chen SF, Wang FJ, and Liu W
- Subjects
- Acute Disease, Adolescent, Adult, Child, Child, Preschool, Creatine Kinase metabolism, Creatine Kinase, MB Form, Electrocardiography, Female, Heart drug effects, Heart physiopathology, Humans, Isoenzymes metabolism, Male, Middle Aged, Occupational Diseases chemically induced, Occupational Diseases metabolism, Troponin T metabolism, Ammonia poisoning, Myocardium pathology, Occupational Diseases diagnosis
- Abstract
Objective: To find a better index for detecting myocardial lesion in patients with acute ammonia poisoning., Methods: Cardiac troponin T (cTnT), creatine kinase (CK), creatine kinase-MB isoenzyme (CK-MB), and electrocardiogram (ECG) were determined and compared in patients with acute ammonia poisoning and healthy controls., Results: In severe ammonia poisoning patients, the levels of cTnT [(1.285 +/- 2.650) micro g/L], CK [(257.636 +/- 362.719) IU/L], CK-MB [(20.909 +/- 19.770) IU/L] were significantly higher than those in healthy control [(0.035 +/- 0.014) micro g/L, (82.050 +/- 36.302) IU/L, (8.350 +/- 2.455) IU/L respectively, P < 0.05]. The levels of cTnT, CK and CK-MB in mild ammonia poisoning patients [(0.039 +/- 0.016) micro g/L, (78.200 +/- 28.401) IU/L and (8.467 +/- 2.669) IU/L respectively], and moderate ammonia poisoning patients [(0.054 +/- 0.043) micro g/L, (99.786 +/- 71.941) IU/L and (9.429 +/- 3.857) IU/L were not significantly different from those of healthy controls (P > 0.05)]. cTnT positive detection rate (68.2%) was significantly higher than CK (36.4%), CK-MB (31.2%) and ECG (31.2%) (P < 0.05)., Conclusion: cTnT is a better index to detect myocardial lesion in severe ammonia poisoning.
- Published
- 2003