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1. Biochemical indicator for evaluation of connective tissue abnormalities in Menkes' disease.

Author

Kodama H, Sato E, Yanagawa Y, Ozawa H, and Kozuma T

Subjects
Biomarkers urine, Connective Tissue Diseases etiology, Humans, Infant, Amino Acids urine, Connective Tissue Diseases diagnosis, Menkes Kinky Hair Syndrome complications
Abstract

Metabolites of collagen metabolism were analyzed in patients with Menkes' disease. The urinary deoxypyridinoline level was significantly low in the patients with Menkes' disease, indicating that it is a good marker of lysyl oxidase activity, which is related to the connective tissue abnormalities.

Published
2003
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