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1. Nitrazepam Synthesized by Amination of 2-(2-Chloroacetamido)-5-nitrobenzophenone with Hexamethylenetetramine.

Author

Anikeev, V. N., Petrunin, A. I., Kilin, M. T., and Guss, F. V.

Subjects
*AMINATION, *BENZODIAZEPINES, *REACTION mechanisms (Chemistry), *PHARMACEUTICAL chemistry, *PHARMACOLOGY, *ANALYTICAL chemistry
Abstract

Studies the nitrazepam synthesized by amination of 2-(2-chloroacetamido)-5-nitrobenzophenone with hexamethylenetetramine. Reaction mechanism of hexamine; Effect of the molar ratio of ammonium chloride to 2-(2-chloroacetamido)-5-benzophenone on the yield of nitrazepam; Effect of the moral ratios of heximine.

Published
2004
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