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1. An expedient synthesis of maraviroc (UK-427,857) via C–H functionalization.

Author

Bedell, T. Aaron, Hone, Graham A.B., Du Bois, Justin, and Sorensen, Erik J.

Subjects
*MARAVIROC (Drug), *CARBON-hydrogen bonds, *CHEMOKINE receptors, *PROPANOLS, *ORGANIC synthesis, *AMINATION
Abstract

A new, concise synthesis of the CCR-5 receptor antagonist maraviroc (UK-427,857) from 3-phenyl-1-propanol has been completed in four steps featuring a site-selective C–H functionalization. [ABSTRACT FROM AUTHOR]

Published
2015
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