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1. Silica-Supported 2,4,6-Trichloro-1,3,5-triazine as an Efficient Reagent for Direct Conversion of Carboxylic Acids to Amides Under Solvent-Free Conditions.

Author

Khalafi-Nezhad, Ali, Zare, Abdolkarim, Parhami, Abolfath, Rad, Mohammad Navid Soltani, and Nejabat, Gholam Reza

Subjects
*CARBOXYLIC acids, *ORGANIC acids, *AMIDES, *AMMONIUM salts, *TRIAZINES
Abstract

A very simple and efficient solvent-free method for the direct conversion of carboxylic acids to primary, secondary, tertiary alkyl, and aromatic amides in the presence of the corresponding ammonium salts, silica-supported 2,4,6-trichloro-1,3,5-triazine, and triethylamine is described. The reactions proceed rapidly at room temperature, and the products are obtained in moderate to excellent yields. [ABSTRACT FROM AUTHOR]

Published
2007
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