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Research data infrastructures form the cornerstone in both cyber and physical spaces, driving the progression of the data-intensive scientific research paradigm. This opinion paper presents an overview of global research data infrastructure, drawing insights from national roadmaps and strategic documents related to research data infrastructure. It emphasizes the pivotal role of research data infrastructures by delineating four new missions aimed at positioning them at the core of the current scientific research and communication ecosystem. The four new missions of research data infrastructures are: (1) as a pioneer, to transcend the disciplinary border and address complex, cutting-edge scientific and social challenges with problem- and data-oriented insights; (2) as an architect, to establish a digital, intelligent, flexible research and knowledge services environment; (3) as a platform, to foster the high-end academic communication; (4) as a coordinator, to balance scientific openness with ethics needs. [ABSTRACT FROM AUTHOR]