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Patch testing was done according to standard guidelines5 with the LUS patch test and five additional substances (97 patients) and the EBS (52 patients). These patients should be patch tested routinely with both LUS and EBS to exclude topical treatment that may delay wound healing. Keywords: allergic contact dermatitis; leg ulcers; patch testing; test series; topical drugs EN allergic contact dermatitis leg ulcers patch testing test series topical drugs 470 472 3 05/06/21 20210601 NES 210601 Contact allergy (CA) is prevalent in patients with chronic leg ulcers (CLUs) due to venous stasis1 and may delay wound healing. [Extracted from the article]

Guinea-pigs previously sensitized to dinitrochlorobenzene (DNCB) were topically treated with 8-methoxypsoralen solution and longwave ultraviolet light (PUVA). The animals showed moderate or no clinical and microscopic responses to an elicitation dose of DNCB given immediately after the period of treatment. Exposure to ultraviolet light or psoralen alone did not affect the allergic response. Ten days after PUVA treatment there was a normal eczematous reaction after application of DNCB. [ABSTRACT FROM AUTHOR]

Delayed hypersensitivity has been reported from vaccines containing aluminium and from hyposensitization treatment. Nickel-sensitive patients may develop allergic contact dermatitis on the hands from frequent contact with coins. This article reports a case of contact urticaria from aluminium and nickel in the same patient. A 19-year old student had a previous history of stress-provoked asthma, allergy to dogs and periodic hand eczema. In 1990, she developed a sever skin reaction when in direct contact with certain metals. She could neither hold coins in the palm of her hand, nor touch metal metal door handles and bannisters without a reaction.