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The article discusses a method for the stereoselective synthesis of the naturally occurring dihydropyranone rugulactone. The key steps of the synthesis begins from 3-phenylpropan-1-ol using Maruoka allylation and ring-closing metathesis. The retrosynthetic analysis suggests that rugulactone can be synthesized from the keto ester, which can be obtained from the alkenol generated through an alkyne from 3-phenylpropan-1-ol.

Bromination of alkenes and alkynes has efficiently been carried out at room temperature in short reaction times using KBr and diacetoxy iodobenzene in CH2Cl2-H2O (1:1) to prepare the corresponding trans-dibromo compounds in excellent yields. [ABSTRACT FROM AUTHOR]

A mild and efficient method has been developed for the synthesis of alkyl and alkenyl iodides from alkenes and alkynes using polymethylhydrosiloxane (PMHS) and iodine in chloroform at room temperature. The reagent system generates hydrogen iodide which regioselectively adds to the alkenes and alkynes. [ABSTRACT FROM AUTHOR]