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An unexpected and efficient domino reaction of N-sulfonyl-1-aza-1,3-dienes with 2-halo-1,3-dicarbonyl compounds to synthesize differently substituted 2,3-dihydrofuran derivatives with excellent regio-, chemo-, and stereoselectivity in moderate to good yields was developed. In this transformation, broad substrate scope was demonstrated, and a plausible mechanism for this novel domino reaction was given. [ABSTRACT FROM AUTHOR]

Abstract: A series of functionalized spiro 1,4-benzoxazine oxindole derivatives were obtained in moderate to good yields via a domino Mannich-alkylation of α-halocarbonyl compounds with imines under mild conditions. [Copyright &y& Elsevier]

An abstract of the article "Synthesis of 2,3-Dihydrothieno(2,3-b)quinolines and Thieno(2,3-b)-quinolines via an Unexpected Domino Aza-MBH/Alkylation/Aldol Reaction" by Pei-Shun Wei and colleagues is presented.

The reaction proceeds under mild conditions and allows the preparation of the title compounds on a gram scale. [ABSTRACT FROM AUTHOR]

A new domino alkylation-cyclization-air oxidation of 2-halo-1,3-dicarbonyl compounds such as (II) and (V) with 2-aminophenols (I) is developed. [ABSTRACT FROM AUTHOR]