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Start Over Author "Shen, Xiuping" Topic alanine aminotransferase (alt)
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1. Integrated systems toxicology approaches identified the possible involvement of ABC transporters pathway in erythromycin estolate-induced liver injury in rat.

Author

Lu, Xiaoyan, Tian, Yu, Lian, Xueping, Jin, Yachao, Jin, Tingting, Zhao, Qinqin, Hu, Bin, Shen, Xiuping, and Fan, Xiaohui

Subjects
*TOXICOLOGY, *ATP-binding cassette transporters, *ERYTHROMYCIN, *LIVER injuries, *LABORATORY rats, *OXIDATIVE stress, *ANTICHOLESTEREMIC agents
Abstract

Highlights: [•] Integrated analysis of multi-omics datasets yields insight into EE liver toxicity. [•] Cholestasis and oxidative stress are involved in EE-induced liver injury. [•] Anti-cholestatic adaptive mechanism is mediated through ABC transporters pathway. [ABSTRACT FROM AUTHOR]

Published
2014
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