1. Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis.
- Author
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Reilly, John, Zhao, Zhiguo, Shashaty, Michael, Koyama, Tatsuki, Jones, Tiffanie, Anderson, Brian, Ittner, Caroline, Dunn, Thomas, Miano, Todd, Oniyide, Oluwatosin, Balmes, John, Matthay, Michael, Calfee, Carolyn, Christie, Jason, Meyer, Nuala, and Ware, Lorraine
- Subjects
Acute lung injury ,Acute respiratory distress syndrome ,Air pollution ,Sepsis ,Humans ,Air Pollutants ,Air Pollution ,Environmental Pollutants ,Nitrogen Dioxide ,Prospective Studies ,Critical Illness ,Particulate Matter ,Respiratory Distress Syndrome ,Sepsis - Abstract
PURPOSE: Exposures to ambient air pollutants may prime the lung enhancing risk of acute respiratory distress syndrome (ARDS) in sepsis. Our objective was to determine the association of short-, medium-, and long-term pollutant exposures and ARDS risk in critically ill sepsis patients. METHODS: We analyzed a prospective cohort of 1858 critically ill patients with sepsis, and estimated short- (3 days), medium- (6 weeks), and long- (5 years) term exposures to ozone, nitrogen dioxide (NO2), sulfur dioxide (SO2), carbon monoxide (CO), particulate matter
- Published
- 2023