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Your search keyword '"Kovalenko MA"' showing total 2 results
Start Over Author "Kovalenko MA" Topic air pollutants
2 results on '"Kovalenko MA"'

1. [Relationship of structural-functional (histological and cytological) parameters with cytogenetic and cytotoxic ones in the evaluation of the influence of environmental factors on the organism].

Author

Beliaeva NN, Sycheva LP, Zhurkov VS, Altaeva AA, Ponomareva OIu, Budarina OV, and Kovalenko MA

Subjects
Administration, Oral, Adolescent, Animals, Child, Cytogenetic Analysis, Epithelial Cells drug effects, Epithelial Cells pathology, Humans, Lethal Dose 50, Leukocyte Count, Leukocytes drug effects, Leukocytes pathology, Male, Micronuclei, Chromosome-Defective chemically induced, Mouth Mucosa pathology, Nasal Mucosa pathology, Rats, Thyroid Gland pathology, Thyroid Gland surgery, Thyroidectomy, Toxicity Tests, Acrylamide toxicity, Air Pollutants toxicity, Chemical Industry, Mouth Mucosa drug effects, Nasal Mucosa drug effects, Thyroid Gland drug effects
Abstract

The paper gives an assessment of the association of structural-functional (histological and cytological), cytogenetic, and cytotoxic changes in the analysis of various exposures of the body during both experiments (oral acrylamide) and population examinations (impact of pulp-and-paper mill waste on the nasal and oral mucosae). The assessment of the association of the study parameters is shown to serve to more completely objectify the pattern of actuating factors.

Published
2011

2. [The cytogenetic status of children living in the vicinity of a pulp-and-paper mill].

Author

Sycheva LP, Ivanov SI, Kovalenko MA, Zhurkov VS, Beliaeva NN, and Antsiferov BM

Subjects
Adolescent, Apoptosis drug effects, Apoptosis genetics, Cell Proliferation drug effects, Child, Child, Preschool, Chromosomes, Human genetics, Environmental Illness chemically induced, Environmental Illness epidemiology, Female, Humans, Karyotyping, Male, Mouth Mucosa drug effects, Nasal Mucosa drug effects, Prevalence, Risk Factors, Russia epidemiology, Air Pollutants adverse effects, Chromosomes, Human drug effects, Environmental Illness genetics, Mouth Mucosa pathology, Nasal Mucosa pathology, Paper
Abstract

To evaluate the cytogenetic and cytotoxic effects of a set of pollutions in the town of Koryazhma, the investigators made a complete karyological analysis (cytogenetic, apoptotic, and indirect proliferation parameters) of buccal and nasal epithelial exfoliative cells in two groups of old school age children living at various distances from a pulp-and-paper mill (PPM). The residential area that is adjacent to the PPM can be considered to be poor in the influence of genotoxic factors since there were 1.6- and 1.65-fold increases in cytogenetic disorders and cells with an atypically shaped nucleus, respectively, with a 1.57-fold reduction in the level of cell apoptosis. Karyological changes were revealed in the nasal mucosa, rather than in the buccal mucosa, which permitted one to recommend for the evaluation of the influence of environmental factors, the impact of ambient air pollution in particular, and to conduct cytogenetic studies on the cells of not only the buccal epithelium (that has been better studied), but also those of the nasal epithelium.

Published
2010

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