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The article examines how effective the Global Fund to Fight AIDS, Tuberculosis and Malaria has been in its five years of operation. In 2002, the Fund was launched to raise, manage, and disburse funds to fight the three major diseases killing people in poor countries, which were HIV/AIDS, tuberculosis, and maleria. According an announcement from the Global Fund in the spring of 2007, the program has treated nearly 3 million turberculosis patients, distributed more than 30 million insecticide-treated bednets, and provided antiretroviral drugs to more than 1 million people infected with HIV. In April 2007, a new executive director to over the management of the organization. The article discusses some of the challenges the new executive director, Michel Kazatchkine, will be facing.

Reports on the complaints of the US National Commission on AIDS regarding the US government's inadequate involvement with the problem of AIDS. Underestimation of the AIDS problem; Call for national prevention initiative; Appointment of an AIDS Coordinator, Kristine M Gebbie.

Reports on the warning from the World Bank concerning the impact of the AIDS epidemic on the economies of developing nations. Estimated number of people to be infected with AIDS virus by the year 2000 from developing countries; Medical costs; Loss of productivity.

Reports that Los Angeles, California Mayor Richard J. Riordan has declared a local state of emergency to the spread of AIDS and HIV infection. State crackdown on the distribution of clean needles to drug users; Riordan's support for responsible needle-exchange programs.