Author: "O'BRIEN, STEPHEN J." / Topic: 3 selected - Searchworks@Jio Institute Digital Library Search Results

Your search keyword '"O'BRIEN, STEPHEN J."' showing total 2 results

Start Over Author "O'BRIEN, STEPHEN J." Topic aids Topic antiviral agents Topic hiv infections

Author: Hendrickson, Sher L., Jacobson, Lisa P., Nelson, George W., Phair, John P., Lautenberger, James, Johnson, Randall C., Kingsley, Lawrence, Margolick, Joseph B., Detels, Roger, Goedert, James J., and O'Brien, Stephen J.
Subjects: *AIDS, *HIV infections, *HIV, *ANTIVIRAL agents, *THERAPEUTICS
Abstract: The article studies the influence of AIDS restriction genes and haplotypes of the CCR5 P1 promoter and RANTES variants among HIV-1 infected patients on highly active antiretroviral therapy in the Multicenter AIDS Cohort Study and the Multicenter Hemophilia Cohort Study. It examines a range of genes that were predicted to influence HAART through various interactions with the HIV life cycle and drug metabolism.
Published: 2008
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Author: Sezgin, Efe, Hendrickson, Sher L., Jabs, Douglas A., Van Natta, Mark L., Lewis, Richard A., Troyer, Jennifer L., and O'Brien, Stephen J.
Subjects: *HIV-positive persons, *AIDS, *CONTRAST sensitivity (Vision), *GENES, *ANTIVIRAL agents, *HIV infections, *RETINAL degeneration, *HIV, *PATIENTS
Abstract: The article presents a study on the effect of host genetics on human immunodeficiency virus neuroretinal disorder (HIV-NRD) in patients with AIDS. It notes the loss of contrast sensitivity that is sufficient to impair reading speed. It mentions the validated AIDS restriction gene variants in evaluating the effect of host genes on HIV-NRD which has been implicated to influence HIV-1 infection, AIDS progression, therapy response, and antiviral drug metabolism.
Published: 2010
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