1. Archaeogenetic analysis of Neolithic sheep from Anatolia suggests a complex demographic history since domestication
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Yasin Gökhan Çakan, Yılmaz Selim Erdal, Füsun Özer, Anders Götherström, Eren Yüncü, Erhan Biçakçi, Pedro Morell Miranda, Mohammad Foad Abazari, Çiğdem Atakuman, Vendela Kempe Lagerholm, Sevgi Yorulmaz, N. Ezgi Altınışık, C. Can Bilgin, Özlem Çevik, Maja Krzewińska, Mustafa Özkan, Ali Akbaba, Torsten Günther, Ayshin Ghalichi, Douglas Baird, Johannes A. Lenstra, Louise Martin, İnci Togan, Fokke Gerritsen, Nihan Dilşad Dağtaş, Gözde Atağ, Javad Hoseinzadeh, Evangelia Pişkin, Mehmet Somel, Can Yumni Gündem, Ekin Sağlıcan, Onur Özer, Sinan Can Açan, Gülşah Merve Kılınç, Dilek Koptekin, Erinç Yurtman, Kıvılcım Başak Vural, Reyhan Yaka, Rana Özbal, Damla Kaptan, Müge Şevketoğlu, Elif Surer, Art and Culture, History, Antiquity, CLUE+, Özbal, Rana (ORCID 0000-0001-6765-2765 & YÖK ID 55583), Yurtman, Erinç, Özer, Onur, Yüncü, Eren, Dağtaş, Nihan Dilşad, Koptekin, Dilek, Çakan, Yasin Gökhan, Özkan, Mustafa, Akbaba, Ali, Kaptan, Damla, Atağ, Gözde, Vural, Kıvılcım Başak, Gündem, Can Yümni, Martin, Louise, Kılınç, Gülşah Merve, Ghalichi, Ayshin, Açan, Sinan Can, Yaka, Reyhan, Sağlıcan, Ekin, Lagerholm, Vendela Kempe, Krzewinska, Maja, Gunther, Torsten, Miranda, Pedro Morell, Pişkin, Evangelia, Sevketoğlu, Müge, Bilgin, C. Can, Atakuman, Ciğdem, Erdal, Yılmaz Selim, Sürer, Elif, Altınışık, N. Ezgi, Lenstra, Johannes A., Yorulmaz, Sevgi, Abazari, Mohammad Foad, Hoseinzadeh, Javad, Baird, Douglas, Bıcakcı, Erhan, Çevik, Özlem, Gerritsen, Fokke, Gotherstrom, Anders, Somel, Mehmet, Togan, İnci, Özer, Füsun, College of Social Sciences and Humanities, Department of Archeology and History of Art, and One Health Toxicologie
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Turkey ,QH301-705.5 ,Population genetics ,Demographic history ,Medicine (miscellaneous) ,Introgression ,Zoology ,Biochemistry ,DNA, Mitochondrial ,Mitochondrial-DNA ,Ancient DNA ,Origins ,Sequence ,Genomes ,Agriculture ,Management ,Emergence ,Lineages ,Farmers ,Article ,Evolutionary genetics ,General Biochemistry, Genetics and Molecular Biology ,Evolutionsbiologi ,Domestication ,Bronze Age ,Genetics ,Animals ,Biology (General) ,Genetik ,DNA, Ancient ,Innovation ,Sheep, Domestic ,Demography ,Cell Nucleus ,Evolutionary Biology ,Polymorphism, Genetic ,Epipaleolithic ,Agricultural and Biological Sciences(all) ,Biochemistry, Genetics and Molecular Biology(all) ,Genomics ,Archaeology ,Genetic structure ,and Infrastructure ,SDG 9 - Industry, Innovation, and Infrastructure ,General Agricultural and Biological Sciences ,SDG 9 - Industry ,Genetics and Molecular Biology(all) ,Biology ,Multidisciplinary sciences ,Life sciences ,Biomedicine ,Science and technology ,Human mitochondrial DNA haplogroup - Abstract
Sheep were among the first domesticated animals, but their demographic history is little understood. Here we analyzed nuclear polymorphism and mitochondrial data (mtDNA) from ancient central and west Anatolian sheep dating from Epipaleolithic to late Neolithic, comparatively with modern-day breeds and central Asian Neolithic/Bronze Age sheep (OBI). Analyzing ancient nuclear data, we found that Anatolian Neolithic sheep (ANS) are genetically closest to present-day European breeds relative to Asian breeds, a conclusion supported by mtDNA haplogroup frequencies. In contrast, OBI showed higher genetic affinity to present-day Asian breeds. These results suggest that the east-west genetic structure observed in present-day breeds had already emerged by 6000 BCE, hinting at multiple sheep domestication episodes or early wild introgression in southwest Asia. Furthermore, we found that ANS are genetically distinct from all modern breeds. Our results suggest that European and Anatolian domestic sheep gene pools have been strongly remolded since the Neolithic., Yurtman, Özer, Yüncü et al. provide an ancient DNA data set to demonstrate the impact of human activity on the demographic history of domestic sheep. The authors demonstrate that there may have been multiple domestication events with notable changes to the gene pool of European and Anatolian sheep since the Neolithic.
- Published
- 2021
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