Search

Your search keyword '"Siel Depestele"' showing total 3 results
Start Over Author "Siel Depestele" Topic aging
3 results on '"Siel Depestele"'

1. Aging and Complexity Effects on Hemisphere-Dependent Movement-Related Beta Desynchronization during Bimanual Motor Planning and Execution

Author

Sybren Van Hoornweder, Diego Andres Blanco-Mora, Siel Depestele, Kim van Dun, Koen Cuypers, Stefanie Verstraelen, and Raf Meesen

Subjects
electroencephalography, aging, bimanual coordination, interlimb coordination, motor planning, motor execution, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

With aging comes degradation of bimanual movement performance. A hallmark feature of bimanual movements is movement-related beta desynchronization (MRBD), an attenuation in the amplitude of beta oscillations associated with sensorimotor activation. Here, we investigated MRBD in 39 healthy adults (20 younger and 19 older adults) in frontal, central, and parietal regions across both hemispheres, during the planning and execution of a bimanual tracking task. Task accuracy decreased with age and during more difficult conditions when both hands had to move at different relative speeds. MRBD was mostly situated in the central region, and increased in older versus younger adults during movement execution but not planning. Irrespective of age, motor planning and execution were associated with increased MRBD in the left and right hemispheres, respectively. Notably, right central MRBD during motor planning was associated with bimanual task performance, particularly in older adults. Specifically, persons who demonstrated high MRBD during motor planning performed better on the bimanual tracking task. Our results highlight the importance of lateralized MRBD during motor planning, thereby shining new light on previous research and providing a promising avenue for future interventions.

Published
2022
Full Text
View/download PDF

2. Age-related changes in midfrontal theta activity during steering control: A driving simulator study

Author

Siel Depestele, Kim van Dun, Stefanie Verstraelen, Veerle Ross, Sybren Van Hoornweder, Kris Brijs, Tom Brijs, Stephan Getzmann, and Raf Meesen

Subjects
Aging, General Neuroscience, Neurology (clinical), Geriatrics and Gerontology, Developmental Biology
Abstract

Motor control, a ubiquitous part of driving, requires increased cognitive controlled processing in older adults relative to younger adults. However, the influence of aging on motor-related neural mechanisms in the context of driving has rarely been studied. The present study aimed to identify age-related changes in cognitive control and attention allocation during a simulated steering task, using electroencephalography. Midfrontal theta, a marker for cognitive control, and posterior alpha power, a marker for attention allocation, were measured in a total of 26 young, 25 middle-aged, and 28 older adults. By adapting driving speed, the difficulty level of this steering task was individualized for each participant. Results show age-related changes in midfrontal theta power, but not in posterior alpha power, despite similar steering accuracy across age groups. Specifically, only younger and, to a lesser extent, middle-aged adults exhibited increased theta power while driving through more demanding curved segments relative to straight segments. In contrast, theta power upregulation was absent in older adults, suggesting a saturation of cognitive resources while driving, possibly due to a limitation in resource capacity, or less automatic motor-related neural processing.

Published
2023
Full Text
View/download PDF

3. Causal involvement of DLPFC during bimanual coordination in older adults - an rTMS study

Author

Stefanie Verstraelen, Koen Cuypers, Kim van Dun, Hakuei Fujiyama, Siel Depestele, Julie Duque, Raf Meesen, Oron Levin, Stephan P. Swinnen, VERSTRAELEN, Stefanie, CUYPERS, Koen, Duque, Julie, DEPESTELE, Siel, VAN DUN, Kim, Fujiyama, Hakuei, Levin, Oron, Swinnen, Stephan P., and MEESEN, Raf

Subjects
business.industry, General Neuroscience, medicine.medical_treatment, Aging, bimanual coordination, dorsolateral prefrontal cortex (DLPFC), Interhemispheric interaction, repetitive transcranial magnetic stimulation (rTMS), behavioral disciplines and activities, Dorsolateral prefrontal cortex, Transcranial magnetic stimulation, medicine.anatomical_structure, nervous system, mental disorders, medicine, business, human activities, Neuroscience, psychological phenomena and processes
Abstract

The role of the dorsolateral prefrontal cortex (DLPFC) in the regulation of bimanual coordination appears to become crucial with aging. Age-related changes in the involvement of the DLPFC in bimanual coordination were studied by using disruptive repetitive TMS (rTMS), inducing a transient lesion in this brain structure. Neurophysiological as well as behavioral effects of suppressing DLPFC during the preparation and execution of a bimanual task were studied in 41 healthy adults (young and old). Specifically, we combined short-train rTMS with single pulse TMS to examine the effect of DLPFC suppression on the interhemispheric projection to the contralateral primary motor cortex (M1) during motor preparation. Findings revealed that compromised interhemispheric DLPFC-M1 disinhibition during motor preparation in older adults resulted in less accurate bimanual performance. The altered DLPFC-M1 interaction in older adults appeared to result from a decline in local inhibitory mechanisms in the DLPFC. In addition, the induction of DLPFC suppression affected task accuracy, but not movement stability in both age groups. Taken together, these results suggest that DLPFC acts as a key regulator in the control of bimanual movement coordination.

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results