1. Smoking, drinking, sleeping habits, and other lifestyle factors and the risk of systemic lupus erythematosus in Japanese females: findings from the KYSS study
- Author
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Asae Oura, Kazushi Okamoto, Takashi Abe, Saburo Ide, Yasuhisa Sinomura, Osamu Ushiyama, Mine Harada, Naomasa Sakamoto, Hiroshi Tsukamoto, Takahiko Horiuchi, Takao Hotokebuchi, Mitsuru Mori, Hiroko Kodama, Gen Kobashi, Toyoko Asami, Norihiko Nogami, Kohei Nagasawa, Tetsuji Yokoyama, Yoshihiro Miyake, Satoshi Sasaki, Hiromu Suzuki, Masaki Nagai, Hiroki Takahashi, Motohisa Yamamoto, Yutaka Inaba, Yoshifumi Tada, Hisato Tanaka, Masakazu Washio, and Chikako Kiyohara
- Subjects
Adult ,medicine.medical_specialty ,Adolescent ,Alcohol Drinking ,Rheumatology ,Japan ,immune system diseases ,Risk Factors ,Internal medicine ,Statistical significance ,Surveys and Questionnaires ,Epidemiology ,medicine ,Odds Ratio ,Humans ,Lupus Erythematosus, Systemic ,skin and connective tissue diseases ,Child ,Life Style ,Aged ,Lupus erythematosus ,business.industry ,Smoking ,Case-control study ,Age Factors ,Odds ratio ,Middle Aged ,medicine.disease ,Lifestyle factors ,Increased risk ,Case-Control Studies ,Immunology ,Female ,business ,Sleep ,Demography - Abstract
Many risk factors have been proposed for systemic lupus erythematosus (SLE). However, there is little information about the relationship between lifestyles and SLE in Japan. Two case control studies were conducted in Kyushu, southern Japan, and in Hokkaido, northern Japan, to examine the relationship between lifestyles and development of SLE in females. The participants were 78 patients and 329 controls in Kyushu and 35 patients and 188 controls in Hokkaido. Smoking was associated with an increased risk of SLE after adjusting for age in both regions. However, in Hokkaido, this association between smoking and SLE did not reach statistical significance after adjusting for alcohol drinking. The present study suggests that smoking may increase the risk of SLE among Japanese females.
- Published
- 2006