1. Age-Specific Incidence Rates for Norovirus in the Community and Presenting to Primary Healthcare Facilities in the United Kingdom.
- Author
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O’Brien, Sarah J., Donaldson, Anna L., Iturriza-Gomara, Miren, Tam, Clarence C., and O'Brien, Sarah J
- Subjects
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AGE distribution , *COMPARATIVE studies , *EPIDEMICS , *FECES , *GASTROENTERITIS , *LONGITUDINAL method , *RESEARCH methodology , *MEDICAL cooperation , *PRIMARY health care , *RESEARCH , *RESEARCH funding , *RNA viruses , *EVALUATION research , *DISEASE incidence , *ACUTE diseases , *NOROVIRUS diseases - Abstract
In a prospective, population-based cohort study and a study of primary-healthcare consultations, we had a rare opportunity to estimate age-specific rates of norovirus-associated infectious intestinal disease in the United Kingdom. Rates in children aged <5 years were significantly higher than those for other age groups in the community (142.6 cases per 1000 person-years [95% confidence interval {CI}, 99.8-203.9] vs 37.6 [95% CI, 31.5-44.7]) and those for individuals presenting to primary healthcare (14.4 cases per 1000 person-years [95% CI, 8.5-24.5] vs 1.4 [95% CI, .9-2.0]). Robust incidence estimates are crucial for vaccination policy makers. This study emphasises the impact of norovirus-associated infectious intestinal disease, especially in children aged <5 years. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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