Delo obravnava spremembe rabe tal v pomurski statistični regiji v obdobju med letoma 2000 in 2017 in odvisnosti teh od izbranih naravnogeografskih in družbenogeografskih kazalcev. Spremembe rabe tal so vrednotene iz vidika izkoriščanja in ohranjanja kmetijskih potencialov regije, ki so med največjimi v Sloveniji. Obravnavane so razlike v splošnih spremembah rabe tal, v smereh sprememb, spremembe v odvisnosti od nadmorskih višin, funkcijskih naklonov, ekspozicij, pedoloških enot, talnega števila, strateško pomembnih območij za kmetijstvo in pridelavo ter v odvisnosti od mikroregij. Pri spremembah so posebej izpostavljene negativne smeri sprememb, ki kažejo izrazite procese ozelenjevanja, zaraščanja, ogozdovanja in pozidave obdelovalnih oblik rabe tal, med katere spadajo njive in vrtovi, vinogradi, sadovnjaki in ostali trajni nasadi. V splošnem se v regiji zmanjšuje število obdelovalnih površin, predvsem njiv z vrtovi in vinogradov, vse bolj pa se širijo neobdelovalne oblike rabe tal, predvsem zemljišča v zaraščanju, gozdovi ter pozidane in sorodne površine. Te spremembe niso v celoti odvisne od naravnogeografskih pogojev, temveč v veliki meri na te vplivajo tudi socio-ekonomski kazalci gibanje števila prebivalstva, povprečne starosti, indeksa staranja, gibanja števila kmetijskih gospodarstev in gibanje velikosti posestev na kmetijsko gospodarstvo. V splošnem tudi v analizi teh ugotavljamo negativne trende, ki jih lahko povezujemo z neugodnimi trendi v spreminjanju rabe tal. This work deals with the changes of land use in the Pomurje statistical region between the years 2000 and 2017, and with the dependency of chosen natural-geographical and socio-geographical indicators. The changes in land use are valued from the point of view of exploitation and conservation of agricultural potentials of the region, which are among the largest in Slovenia. This master’s thesis discusses the differences in general changes of land use, the directions of changes, changes of the dependency to altitude, functional inclination, exposition, pedological units, floor value, ground value, strategically important areas for agriculture and cultivation, with the dependence on micro-regions. Negative direction of changes are exposed, since they show striking processes of greening, overgrowth, afforestation and the sealing of processing forms of land use, which are fields and gardens, vineyards, orchards and other permanent plantations. In overall, there are signs of arable land reduction, especially fields with gardens and vineyards, and the spreading of non-arable land, especially land in overgrowth, forests and built-up and related land. These changes are not entirely dependent on natural-geographical conditions, but are largely influenced by socio-economic indicators. In this thesis I have analysed changes in population, average population age, aging index, the changes in numbers of agricultural holdings and the changes in the sizes of agricultural estates. While analysing the latter, we have found negative trends that can be connected to unfavourable trends in land use.