1. Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research’s Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases
- Author
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William T. Cefalu, Dana K. Andersen, Guillermo Arreaza-Rubín, Christopher L. Pin, Sheryl Sato, C. Bruce Verchere, Minna Woo, Norman D. Rosenblum, Norman Rosenblum, William Cefalu, Christine Dhara, Stephen P. James, Mary-Jo Makarchuk, Bruce Verchere, Alvin Powers, Jennifer Estall, Corrine Hoesli, Jeffrey Millman, Amelia Linnemann, James Johnson, Meredith Hawkins, Anna Gloyn, Mark O. Huising, Richard K.P. Benninger, Joana Almaça, Rebecca L. Hull-Meichle, Patrick MacDonald, Francis Lynn, Juan Melero-Martin, Eiji Yoshihara, Cherie Stabler, Maike Sander, Carmella Evans-Molina, Feyza Engin, Peter Thompson, Anath Shalev, Maria J. Redondo, Kristen Nadeau, Melena Bellin, Miriam S. Udler, John Dennis, Satya Dash, Wenyu Zhou, Michael Snyder, Gillian Booth, Atul Butte, and Jose Florez
- Subjects
Gerontology ,Canada ,Chronic condition ,Endocrinology, Diabetes and Metabolism ,MEDLINE ,Diabetes treatment ,Pediatrics ,Perspectives in Care ,Endocrinology ,Diabetes mellitus ,Diabetes Mellitus ,Internal Medicine ,medicine ,Humans ,Precision Medicine ,Clinical care ,Advanced and Specialized Nursing ,business.industry ,General Medicine ,medicine.disease ,Precision medicine ,United States ,Phenotype ,National Institutes of Health (U.S.) ,National Institute of Diabetes and Digestive and Kidney Diseases (U.S.) ,Cohort ,Perspectives in Diabetes ,business - Abstract
One hundred years have passed since the discovery of insulin—an achievement that transformed diabetes from a fatal illness into a manageable chronic condition. The decades since that momentous achievement have brought ever more rapid innovation and advancement in diabetes research and clinical care. To celebrate the important work of the past century and help to chart a course for its continuation into the next, the Canadian Institutes of Health Research’s Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases recently held a joint international symposium, bringing together a cohort of researchers with diverse interests and backgrounds from both countries and beyond to discuss their collective quest to better understand the heterogeneity of diabetes and thus gain insights to inform new directions in diabetes treatment and prevention. This article summarizes the proceedings of that symposium, which spanned cutting-edge research into various aspects of islet biology, the heterogeneity of diabetic phenotypes, and the current state of and future prospects for precision medicine in diabetes.
- Published
- 2021