1. [Prognosis of infectious endocarditis]
- Author
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Hamda K, Ben, F, Betbout, F, Addad, H, Gamra, F, Maatouk, Z, Dridi, M A, Zidi, R, Hammouda, and Farhat M, Ben
- Subjects
Adult ,Male ,Analysis of Variance ,Tunisia ,Adolescent ,Endocarditis, Bacterial ,Middle Aged ,Prognosis ,Disease-Free Survival ,Hospitals, University ,Treatment Outcome ,Predictive Value of Tests ,Risk Factors ,Child, Preschool ,Disease Progression ,Humans ,Female ,Hospital Mortality ,Morbidity ,Child ,Echocardiography, Transesophageal ,Aged ,Proportional Hazards Models ,Retrospective Studies - Abstract
To study clinical course and prognostic factors of infective endocarditis.Infective endocarditis was identified in 126 consecutive patients (criteria of DURACK). Of these, 73 were male, mean age was 29.9 + 15 years, 98 (77.7%) had past history of cardiac disease. The evolution has been marked by 38 deaths (30%) in spite of the recourse to surgery (69 patients). The mean follow-up period was 52 months, the event-free survival was 61% at 5 years.By univariate analysis the predictors of bad prognosis: Large vegetations10 mm, delay of apyrexia10 days presence of a neurological accident and the absence of surgical treatment. Multivariate analysis: Vegetation10 mm (OR 1.97, 1-4.1, p = 0.05), presence of a neurological accident (OR:2.76, 1.32-5.76, p = 0.007) and the absence of surgical treatment (OR: 5.03, 2-11.4, p0.001).Infective endocarditis remains a serious affection, identification of patients with poor prognosis should lead to early surgical referral: this attitude provides good immediate and long-term results.
- Published
- 2003