1. Risk Factors for Death from Invasive Pneumococcal Disease, Europe, 2010
- Author
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Navarro Torné, Adoración, Dias, Joana Gomes, Hruba, Frantiska, Lopalco, PIETRO LUIGI, Pastore Celentano, Lucia, Amato Gauci, Andrew J., Sabbe, Martine, Detcheva, Antoaneta, Georgieva, Teodora, Bagatzouni, Despo Pieridou, Křížová, Pavla, Valentiner Branth, Palle, Fenoll, Asunción, Virolainen Julkunen, Anni, Georgakopoulou, Theano, Tzanakaki, Georgina, Melles, Márta, Vickers, Imelda, Cotter, Suzanne, Humphreys, Hilary, Kristinsson, Karl G, Caporali, Maria Grazia, D’Ancona, Fortunato Paolo, Iannazzo, Stefania, Pantosti, Annalisa, Galajeva, Jelena, Caruana, Paul, Melillo, Jackie Maistre, Fenech, Tanya Melillo, De Melker, Hester, Knol, Mirjam, Van Der Ende, Arie, Steinbakk, Martin, Vestrheim, Didrik F, Hryniewicz, Waleria, Kuch, Alicja, Paradowska Stankiewicz, Iwona, Skoczynska, Anna, Pana, Marina, Henriques Normak, Birgitta, Kraigher, Alenka, Sočan, Maja, Hupkova, Helena, Macdonald, Eisin, Slack, Mary P. E., Waight, Pauline A., Amsterdam institute for Infection and Immunity, and Medical Microbiology and Infection Prevention more...
- Subjects
Serotype ,Male ,History ,Streptococcus pneumonia ,pneumococcal vaccine ,Epidemiology ,lcsh:Medicine ,medicine.disease_cause ,Pneumococcal Vaccines ,Risk Factors ,80 and over ,Young adult ,bacteria ,Child ,Aged, 80 and over ,Streptococcus pneumoniae invasive pneumococcal disease ,antimicrobial drug resistance ,Incidence (epidemiology) ,Medicine (all) ,Incidence ,meningitis ,Middle Aged ,21st Century ,Anti-Bacterial Agents ,Adolescent ,Adult ,Aged ,Child, Preschool ,Europe ,Female ,History, 21st Century ,Humans ,Infant ,Microbial Sensitivity Tests ,Mortality ,Pneumococcal Infections ,Population Surveillance ,Serogroup ,Young Adult ,Streptococcus pneumoniae ,Microbiology (medical) ,Infectious Diseases ,Pneumococcal infections ,Meningitis ,medicine.medical_specialty ,Risk Factors for Death from Invasive Pneumococcal Disease, Europe, 2010 ,invasive pneumococcal disease ,lcsh:Infectious and parasitic diseases ,Internal medicine ,death ,medicine ,lcsh:RC109-216 ,Preschool ,business.industry ,Research ,lcsh:R ,medicine.disease ,respiratory tract diseases ,Pneumococcal vaccine ,Immunology ,business - Abstract
Risk varies by Streptococcus pneumoniae serotype., We studied the possible association between patient age and sex, clinical presentation, Streptococcus pneumoniae serotype, antimicrobial resistance, and death in invasive pneumococcal disease cases reported by 17 European countries during 2010. The study sample comprised 2,921 patients, of whom 56.8% were men and 38.2% were >65 years of age. Meningitis occurred in 18.5% of cases. Death was reported in 264 (9.0%) cases. Older age, meningitis, and nonsusceptibility to penicillin were significantly associated with death. Non–pneumococcal conjugate vaccine (PCV) serotypes among children 65 years of age, risk did not differ by serotype. These findings highlight differences in case-fatality rates between serotypes and age; thus, continued epidemiologic surveillance across all ages is crucial to monitor the long-term effects of PCVs. more...
- Published
- 2015