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Start Over Author "Szekely, Tiberiu- Bogdan" Topic adrenocortical carcinoma
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1. Adrenocortical carcinoma: A tumor with poor answer to classic chemotherapy

Author

Sava Alexandra Daniela, Szekely Tiberiu Bogdan, Togănel Cornelia, Vacar Adela, and Gurzu Simona

Subjects
adrenocortical carcinoma, weiss score, familial cancer syndromes, mitotane, Medicine
Abstract

Introduction: Adrenocortical carcinoma (ACC) represents a rare endocrine malignancy being the second most aggressive endocrine cancer after anaplastic thyroid cancer. [1]. While most of them arise sporadically, up to 15% of adult ACC patients are related to germline mutations associated with familial cancer syndromes.[1,2]. Current treatment strategies include surgery as well as systemic therapy with mitotane and chemotherapy.

Published
2023
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