1. [Asymptomatic myocardial ischemia in the dynamics of anaprilin and korinfar treatment].
- Author
-
Volkov VI, Ermakovich II, and Strona VI
- Subjects
- Adult, Angina Pectoris drug therapy, Angina Pectoris physiopathology, Chronic Disease, Circadian Rhythm drug effects, Electrocardiography drug effects, Humans, Monitoring, Physiologic, Myocardial Ischemia physiopathology, Time Factors, Adrenergic beta-Antagonists therapeutic use, Calcium Channel Blockers therapeutic use, Myocardial Ischemia drug therapy, Nifedipine therapeutic use, Propranolol therapeutic use
- Abstract
Overall thirty-eight patients with exertional angina who had episodes of asymptomatic change of position of T-segment were examined. The above patients were divided into two groups: group I was placed on anaprilin treatment (80-120 mg daily), group II received corinfar (60 mg daily). Episodes of asymptomatic ischemia of the myocardium (AIM) showed two peaks in their 24 h-span occurrence, with the greatest number of these being recordable in early morning hours (from six a.m. to noon), somewhat less--within the time span 12 o'clock-0.6 p.m. Anaprilin monotherapy is more effective than corinfar monotherapy in respect to reduction of AIM episodes occurrences. However, corinfar, unlike anaprilin, prevented the appearance of the evening peak of episodes of "silent" ischemia.
- Published
- 1997