1. Cardiac dysfunction in Multisystem Inflammatory Syndrome in Children: An Italian single-center study
- Author
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Savina Mannarino, Irene Raso, Massimo Garbin, Elena Ghidoni, Carla Corti, Sara Goletto, Luisa Nespoli, Sara Santacesaria, Elena Zoia, Anna Camporesi, Francesca Izzo, Dario Dilillo, Laura Fiori, Enza D’Auria, Annalisa De Silvestri, Alberto Dolci, Valeria Calcaterra, and Gianvincenzo Zuccotti
- Subjects
Settore MED/38 - Pediatria Generale e Specialistica ,Adolescent ,Heart Diseases ,SARS-CoV-2 ,Multisystem inflammatory syndrome ,COVID-19 ,Heart ,Stroke Volume ,Pediatrics ,RJ1-570 ,Systemic Inflammatory Response Syndrome ,Ventricular Function, Left ,Italy ,Humans ,RNA, Viral ,Cardiac ,Children ,Child ,Settore BIO/12 - Biochimica Clinica e Biologia Molecolare Clinica ,Retrospective Studies - Abstract
Background Multisystem inflammatory syndrome in children (MIS-C) is a novel condition temporally associated with SARS-CoV2 infection. Cardiovascular involvement is mainly evident as acute myocardial dysfunction in MIS-C. The aim of this study was to describe the cardiac dysfunction in patients with MIS-C, defining the role of severity in the clinical presentations and outcomes in a single cohort of pediatric patients. Methods A single-center retrospective study on patients diagnosed with MIS-C, according to the Center for Disease Control and Prevention (CDC) definition, and referred to Vittore Buzzi Children’s Hospital in Milan from November 2020 to February 2021. Patients were managed according to a local approved protocol. According to the admission cardiac left ventricular ejection fraction (LVEF), the patients were divided into group A (LVEF
- Published
- 2021