1. Malignancy of intraductal papillary neoplasm of the bile duct
- Author
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Alberto Gómez Pérez, Manuel Luis Rodriguez Perálvarez, Javier Manuel Zamora Olaya, and Ana Aparicio Serrano
- Subjects
medicine.medical_specialty ,Abdominal pain ,medicine.medical_treatment ,Malignancy ,Asymptomatic ,Cholangiocarcinoma ,medicine ,Adjuvant therapy ,Hepatectomy ,Humans ,Chemotherapy ,Intraductal papillary mucinous neoplasm ,Bile duct ,business.industry ,Gastroenterology ,General Medicine ,Jaundice ,Middle Aged ,medicine.disease ,medicine.anatomical_structure ,Bile Ducts, Intrahepatic ,Bile Duct Neoplasms ,Female ,Radiology ,Bile Ducts ,medicine.symptom ,business - Abstract
Intraductal papillary neoplasm of the bile duct (IPNB) is an uncommon disease which was first included in the World Health Organization classification of neoplasms in 2010. A 64-year-old female was admitted to the hospital because of a hepatic lesion incidentally diagnosed during acute cholangitis. Abdominal computed tomography (CT) and magnetic resonance imaging (MRI) showed a well delimited 70 mm mass, with a predominant cystic component and hyperenhancement of papillary internal branching, consistent with a hydatid cyst. However, malignancy could not be excluded. The patient rapidly developed an acute abdomen syndrome, thus precluding a liver biopsy. A new urgent CT was performed to rule out a complication of the cystic lesion. A left hepatectomy was performed and the anatomopathological study confirmed the diagnosis of IPNB with a focus of cholangiocarcinoma therein. During follow up, the patient developed peritoneal carcinomatosis, received palliative chemotherapy and finally died.
- Published
- 2022