1. Fitness and fatness are independently associated with markers of insulin resistance in European adolescents; The HELENA Study
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Jiménez Pavón, David, Castillo, Manuel J., Moreno, Luis A., Kafatos, Anthony, Manios, Yannis, Kondaki, Katerine, Béghin, Laurent, Zaccaria, Maria, De Henauw, Stefaan, Widhalm, Kurt, Molnár, Dénes, Sjöström, Michael, González Gross, Marcela, Ruiz, Jonatan R., Moreno LA, Gottrand F, De Henauw S, González Gross M, Gilbert C, Kafatos A, Libersa C, Sánchez J, Kersting M, Sjöstrom M, Molnár D, Dallongeville J, Hall G, Maes L, Scalfi L, Fleta J, Casajús JA, Rodríguez G, Tomás C, Mesana MI, Vicente Rodríguez G, Villarroya A, Gil CM, Ara I, Revenga J, Lachen C, Fernández Alvira J, Bueno G, Lázaro A, Bueno O, León JF, Ma Garagorri J, Bueno M, Rey López JP, Iglesia I, Velasco P, Bel S, Marcos A, Wärnberg J, Nova E, Gómez S, Ligia Díaz E, Romeo J, Veses A, Angeles Puertollano M, Zapatera B, Pozo T, Beghin L, Iliescu C, Von Berlepsch J, Sichert Hellert W, Koeppen E, Molnar D, Erhardt E, Csernus K, Török K, Bokor S, Angster M, Nagy E, Kovács O, Répasi J, Codrington C, Plada M, Papadaki A, Sarri K, Viskadourou A, Hatzis C, Kiriakakis M, Tsibinos G, Sbokos CV, Protoyeraki E, Fasoulaki M, Stehle P, Pietrzik K, Breidenassel C, Spinneker A, Al Tahan J, Segoviano M, Berchtold A, Bierschbach C, Blatzheim E, Schuch A, Pickert P, Castillo Garzón MJ, Gutiérrez Sáinz Á, Ortega Porcel FB, Ruiz Ruiz J, García Artero E, España Romero V, Jiménez Pavón D, Sánchez Muñoz C, Soto V, Chillón P, Heredia JM, Aparicio V, Baena P, Cardia CM, Carbonell A, Arcella D, Catasta G, Censi L, Ciarapica D, Ferrari M, Le Donne C, Leclerq C, Magrì L, Maiani G, Piccinelli R, Polito A, Spada R, Toti E, Montagnese C, De Bourdeaudhuij I, De Vriendt T, Matthys C, Vereecken C, de Maeyer M, Ottevaere C, Huybrechts I, Widhalm K, Phillipp K, Dietrich S, Kubelka B, Boriss Riedl M, Manios Y, Grammatikaki E, Bouloubasi Z, Cook TL, Eleutheriou S, Consta O, Moschonis G, Katsaroli I, Kraniou G, Papoutsou S, Keke D, Petraki I, Bellou E, Tanagra S, Kallianoti K, Argyropoulou D, Kondaki K, Tsikrika S, Karaiskos C, Meirhaeghe A, Bergman P, Hagströmer M, Hallström L, Hallberg M, Poortvliet E, Rizzo N, Beckman L, Wennlöf AH, Patterson E, Kwak L, Cernerud L, Tillgren P, Sörensen S, Sánchez Molero J, Picó E, Navarro M, Viadel B, Enrique Carreres J, Merino G, Sanjuán R, Lorente M, José Sánchez M, Castelló S, Thomas S, Allchurch E, Burguess P, Astrom A, Sverkén A, Broberg A, Masson A, Lehoux C, Brabant P, Pate P, Fontaine L, Sebok A, Kuti T, Hegyi A, Maldonado C, Llorente A, García E, von Fircks H, Hallberg ML, Messerer M, Larsson M, Fredriksson H, Adamsson V, Börjesson I, Fernández L, Smillie L, Wills J, Meléndez A, Benito PJ, Calderón J, Valtueña J, Navarro P, Urzanqui A, Albers U, Pedrero R, Gómez Lorente J.J., VITAGLIONE, PAOLA, Jiménez Pavón, David, Castillo, Manuel J., Moreno, Luis A., Kafatos, Anthony, Manios, Yanni, Kondaki, Katerine, Béghin, Laurent, Zaccaria, Maria, De Henauw, Stefaan, Widhalm, Kurt, Molnár, Déne, Sjöström, Michael, González Gross, Marcela, Ruiz, Jonatan R., Moreno, La, Gottrand, F, De Henauw, S, González Gross, M, Gilbert, C, Kafatos, A, Libersa, C, Sánchez, J, Kersting, M, Sjöstrom, M, Molnár, D, Dallongeville, J, Hall, G, Maes, L, Scalfi, L, Fleta, J, Casajús, Ja, Rodríguez, G, Tomás, C, Mesana, Mi, Vicente Rodríguez, G, Villarroya, A, Gil, Cm, Ara, I, Revenga, J, Lachen, C, Fernández Alvira, J, Bueno, G, Lázaro, A, Bueno, O, León, Jf, Ma Garagorri, J, Bueno, M, Rey López, Jp, Iglesia, I, Velasco, P, Bel, S, Marcos, A, Wärnberg, J, Nova, E, Gómez, S, Ligia Díaz, E, Romeo, J, Veses, A, Angeles Puertollano, M, Zapatera, B, Pozo, T, Beghin, L, Iliescu, C, Von Berlepsch, J, Sichert Hellert, W, Koeppen, E, Molnar, D, Erhardt, E, Csernus, K, Török, K, Bokor, S, Angster, M, Nagy, E, Kovács, O, Répasi, J, Codrington, C, Plada, M, Papadaki, A, Sarri, K, Viskadourou, A, Hatzis, C, Kiriakakis, M, Tsibinos, G, Sbokos, Cv, Protoyeraki, E, Fasoulaki, M, Stehle, P, Pietrzik, K, Breidenassel, C, Spinneker, A, Al Tahan, J, Segoviano, M, Berchtold, A, Bierschbach, C, Blatzheim, E, Schuch, A, Pickert, P, Castillo Garzón, Mj, Gutiérrez Sáinz, Á, Ortega Porcel, Fb, Ruiz Ruiz, J, García Artero, E, España Romero, V, Jiménez Pavón, D, Sánchez Muñoz, C, Soto, V, Chillón, P, Heredia, Jm, Aparicio, V, Baena, P, Cardia, Cm, Carbonell, A, Arcella, D, Catasta, G, Censi, L, Ciarapica, D, Ferrari, M, Le Donne, C, Leclerq, C, Magrì, L, Maiani, G, Piccinelli, R, Polito, A, Spada, R, Toti, E, Vitaglione, Paola, Montagnese, C, De Bourdeaudhuij, I, De Vriendt, T, Matthys, C, Vereecken, C, de Maeyer, M, Ottevaere, C, Huybrechts, I, Widhalm, K, Phillipp, K, Dietrich, S, Kubelka, B, Boriss Riedl, M, Manios, Y, Grammatikaki, E, Bouloubasi, Z, Cook, Tl, Eleutheriou, S, Consta, O, Moschonis, G, Katsaroli, I, Kraniou, G, Papoutsou, S, Keke, D, Petraki, I, Bellou, E, Tanagra, S, Kallianoti, K, Argyropoulou, D, Kondaki, K, Tsikrika, S, Karaiskos, C, Meirhaeghe, A, Bergman, P, Hagströmer, M, Hallström, L, Hallberg, M, Poortvliet, E, Rizzo, N, Beckman, L, Wennlöf, Ah, Patterson, E, Kwak, L, Cernerud, L, Tillgren, P, Sörensen, S, Sánchez Molero, J, Picó, E, Navarro, M, Viadel, B, Enrique Carreres, J, Merino, G, Sanjuán, R, Lorente, M, José Sánchez, M, Castelló, S, Thomas, S, Allchurch, E, Burguess, P, Astrom, A, Sverkén, A, Broberg, A, Masson, A, Lehoux, C, Brabant, P, Pate, P, Fontaine, L, Sebok, A, Kuti, T, Hegyi, A, Maldonado, C, Llorente, A, García, E, von Fircks, H, Hallberg, Ml, Messerer, M, Larsson, M, Fredriksson, H, Adamsson, V, Börjesson, I, Fernández, L, Smillie, L, Wills, J, Meléndez, A, Benito, Pj, Calderón, J, Valtueña, J, Navarro, P, Urzanqui, A, Albers, U, Pedrero, R, and Gómez Lorente, J. J.
- Subjects
Blood Glucose ,Male ,Cross-sectional study ,medicine.medical_treatment ,Body Mass Index ,Insulin ,Age Factor ,Skinfold Thickne ,Adiposity ,Nutrition and Dietetics ,Health Policy ,Age Factors ,Health Survey ,Europe ,Skinfold Thickness ,Cardiorespiratory fitne ,Regression Analysis ,Female ,Waist Circumference ,Human ,medicine.medical_specialty ,Waist ,Adolescent ,Regression Analysi ,Insulin resistance ,Internal medicine ,medicine ,HOMA ,Humans ,Obesity ,Cardiovascular fitness ,Cross-Sectional Studie ,Analysis of Variance ,business.industry ,Body Weight ,Public Health, Environmental and Occupational Health ,nutritional and metabolic diseases ,Cardiorespiratory fitness ,medicine.disease ,Health Surveys ,Body Height ,Total and central body fat ,Endocrinology ,Cross-Sectional Studies ,Glucose ,Physical Fitness ,Pediatrics, Perinatology and Child Health ,Exercise Test ,Physical Fitne ,Insulin Resistance ,business ,Body mass index - Abstract
To examine the independent association of total and central body fat and cardiorespiratory fitness with markers of insulin resistance after controlling for several potential confounders in European adolescents participating in the HELENA-CSS (Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional) study.We conducted a cross sectional study (the HELENA-CSS) which comprised 1053 (12.5-17.5 years) adolescents from 10 European cities. Weight, height, waist circumference and skinfold thickness were measured, and body mass index (BMI) was calculated. Cardiorespiratory fitness was measured by the 20-m shuttle run test. Markers of insulin resistance were fasting insulin and glucose, and homeostasis model assessment (HOMA).HOMA and insulin were positively associated with BMI, skinfolds and waist circumference after controlling for center, age, pubertal status and cardiorespiratory fitness (all P ? 0.01). HOMA and insulin were negatively associated with cardiorespiratory fitness in adolescents with moderate to high levels of total and central body fat (all P ? 0.01).HOMA and insulin were associated with total and central body fat in European adolescents. Moreover, cardiorespiratory fitness explained a part of the HOMA and insulin variance in those adolescents with moderate to high levels of total and central body fat, and also, to some extent, in those with low to middle fat mass.
- Published
- 2011