1. In vitro phytochemical, antibacterial, and antifungal activities of leaf, stem, and root extracts of Adiantum capillus veneris.
- Author
-
Ishaq MS, Hussain MM, Afridi MS, Ali G, Khattak M, Ahmad S, and Shakirullah
- Subjects
- Adiantum anatomy & histology, Anti-Bacterial Agents pharmacology, Antifungal Agents pharmacology, Aspergillus drug effects, Bacteria drug effects, Candida drug effects, Plant Extracts pharmacology, Plant Leaves chemistry, Plant Roots chemistry, Plant Stems chemistry, Adiantum chemistry, Anti-Bacterial Agents chemistry, Antifungal Agents chemistry, Plant Extracts chemistry
- Abstract
Adiantum capillus veneris is a medicinally essential plant used for the treatment of diverse infectious diseases. The study of phytochemical and antimicrobial activities of the plant extracts against multidrug-resistant (MDR) bacteria and medically important fungi is of immense significance. Extracts from the leaves, stems, and roots of Adiantum capillus veneris were extracted with water, methanol, ethanol, ethyl acetate, and hexane and screened for their antimicrobial activity against ten MDR bacterial strains and five fungal strains isolated from clinical and water samples. Ash, moisture, and extractive values were determined according to standard protocols. FTIR (Fourier transform infrared Spectroscopy) studies were performed on different phytochemicals isolated from the extracts of Adiantum capillus Veneris. Phytochemical analysis showed the presence of flavonoids, alkaloids, tannins, saponins, cardiac glycosides, terpenoids, steroids, and reducing sugars. Water, methanol, and ethanol extracts of leaves, stems, and roots showed significant antibacterial and antifungal activities against most of the MDR bacterial and fungal strains. This study concluded that extracts of Adiantum capillus veneris have valuable phytochemicals and significant activities against most of the MDR bacterial strains and medically important fungal strains.
- Published
- 2014
- Full Text
- View/download PDF