1. AMP kinase in exercise adaptation of skeletal muscle.
- Author
-
Jessen N, Sundelin EI, and Møller AB
- Subjects
- Animals, Humans, Adaptation, Physiological physiology, Adenylate Kinase physiology, Exercise physiology, Muscle, Skeletal enzymology
- Abstract
Regular physical exercise has undisputed health benefits in the prevention and the treatment of many diseases. Understanding the mechanisms that regulate adaptations to exercise training therefore has obvious clinical perspectives. Several lines of evidence suggest that the AMP-activated protein kinase (AMPK) has a central role as a master metabolic regulator in skeletal muscle. Exercise is a potent activator of AMPK, and AMPK signaling can play a key part in regulating protein turnover during and after exercise training., (Copyright © 2014 Elsevier Ltd. All rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF