Search

Alveolar soft part sarcoma (ASPS) is a rare soft tissue tumor occurring mainly in the adolescents and young adults. Multimodality treatment has not been effective, and excision remains the mainstay of treatment. Histopathologically, it varies little from case to case. It is composed of organoid aggregates of large polygonal cells with vesicular nuclei and abundant granular, eosinophilic cytoplasm, separated by delicate vascular channels. The line of differentiation of this unique tumor is yet undetermined, although recent advances have led to a better understanding of the genetic events underlying the pathogenesis of this tumor. The histopathological, ultrastructural, immunohistochemical, and genetic aspects of ASPS are discussed. [ABSTRACT FROM AUTHOR]

Embryonal rhabdomyosarcoma, botryoid variant, is a malignant tumor that usually arises in the urinary bladder and other mucosal sites. This is a case of a 4-year-old girl presenting with a mass initially thought to arise within the urinary bladder. Macroscopic and microscopic examination proved that this botryoid rhabdomyosarcoma had its origin within the left ureter. [ABSTRACT FROM AUTHOR]