1. Current Perspectives on Gastric Cancer.
- Author
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Marqués-Lespier JM, González-Pons M, and Cruz-Correa M
- Subjects
- Adenocarcinoma diagnosis, Adenocarcinoma pathology, Adenocarcinoma therapy, Alcohol Drinking, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Antineoplastic Agents, Diet, Gastrectomy, Genetic Predisposition to Disease, Helicobacter pylori, Humans, Metaplasia, Risk Factors, Sex Distribution, Stomach Neoplasms diagnosis, Stomach Neoplasms pathology, Stomach Neoplasms therapy, Trastuzumab, Ramucirumab, Adenocarcinoma epidemiology, Epstein-Barr Virus Infections epidemiology, Gastritis, Atrophic epidemiology, Helicobacter Infections epidemiology, Obesity epidemiology, Occupational Exposure statistics & numerical data, Smoking epidemiology, Stomach Neoplasms epidemiology
- Abstract
Gastric cancer (GC) is third leading cause of cancer-related death. Only 28.3% of new GC cases survive more than 5 years. Although incidence has declined in the United States, an increase is estimated for 2016. Risk factors include sex (risk is higher in men), Helicobacter pylori infection, heredity, and lifestyle. GC is usually diagnosed between the ages of 60-80 years. Prognosis of GC is largely dependent on the tumor stage at diagnosis and classification as intestinal or diffuse type; diffuse-type GC has worse prognosis. Chemoprevention has been shown to decrease risk, but is currently not used clinically., Competing Interests: The authors have no conflict of interest to disclose., (Copyright © 2016 Elsevier Inc. All rights reserved.)
- Published
- 2016
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