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5 results on '"Belous TA"'

1. [The immunohistochemical study of trophoblast beta 1-globulin expression in cancer and in the mucosa of the large intestine].

Author

Pugachev KK, Shimbireva IB, Belous TA, and Frank GA

Subjects
Adult, Colitis, Ulcerative diagnosis, Humans, Immunohistochemistry, Lymphatic Metastasis, Adenocarcinoma diagnosis, Biomarkers, Tumor metabolism, Colon metabolism, Colonic Neoplasms diagnosis, Intestinal Mucosa metabolism, Pregnancy Proteins metabolism, Pregnancy-Specific beta 1-Glycoproteins metabolism
Abstract

The expression of pregnancy-specific beta-1-globulin (SP1) was studied in cancer-affected and nonaffected colon mucosa. The antigen was revealed in 19 out of 50 (38%) cases of carcinoma and in 1 out of 4 cases of ulcerative colitis. SP1 was found neither in noncancer colon mucosa nor in transitional mucosa and adenomas. The antigen was detected in the epithelium and stromal macrophages of carcinoma. SP1-positive cells were located mainly in the sites of tumor invasion. The results allow considering SP1 the tumor marker suitable for immunohistochemical diagnosis of colon cancer.

Published
1992

2. [Cytomorphological criteria of atypical hyperplasia and cancer of the endometrium based on data from a multivariate statistical analysis].

Author

Agamova KA, Starinskiĭ VV, Gladunova ZD, Sidorova NA, Nevskaia EA, Belous TA, Sokolova NV, Gorbenko KE, Puchkov IuG, and Novik VI

Subjects
Adenocarcinoma epidemiology, Adenocarcinoma pathology, Algorithms, Cytodiagnosis, Diagnosis, Computer-Assisted, Diagnosis, Differential, Discriminant Analysis, Endometrial Hyperplasia epidemiology, Endometrial Hyperplasia pathology, Female, Humans, Multivariate Analysis, Uterine Neoplasms epidemiology, Uterine Neoplasms pathology, Adenocarcinoma diagnosis, Endometrial Hyperplasia diagnosis, Uterine Neoplasms diagnosis
Abstract

Multifactorial statistical analysis was used to identify differential diagnostic cytological features of glandular hyperplasia, atypical hyperplasia and well-differentiated adenocarcinoma of the endometrium. Twelve cytological features were identified for calculating linear discriminant function. The effectiveness of the diagnostic algorithm depends upon the diagnostic value of the sample and proficiency of the cytologist.

Published
1991

3. [The proliferative activity of stomach cancer and evaluation of its individual radiosensitivity].

Author

Chissov VI, Sergeeva NS, Dar'ialova SL, Petrov AN, Repina AG, Belous TA, and Pelevina II

Subjects
Adenocarcinoma radiotherapy, Adenocarcinoma, Mucinous radiotherapy, Adult, Aged, Female, Humans, Male, Middle Aged, S Phase physiology, Stomach Neoplasms radiotherapy, Adenocarcinoma physiopathology, Adenocarcinoma, Mucinous physiopathology, Radiation Tolerance physiology, Stomach Neoplasms physiopathology
Abstract

An indirect immunofluorescent method with polyclonal antibodies to thymidine was used to assess the proliferative activity (PA--percent of cells in the S-phase of the cell cycle) of 79 stomach tumors from primary cancer patients. Stomach cancer PA was shown to vary from 0.1 to 69.7%. PA did not depend either on a tumor size or a degree of the involvement of regional lymph nodes. The mean PA of well-differentiated adenocarcinoma was slightly lower (14.9 +/- 4.7%) than that of low differentiated ones. Of 79 patients a tumor process was interpreted as a resectable one in 62. They were given preoperative irradiation at a total focal dose of 36 Gy followed by operation. In addition to initial investigation PA in tumor biopsy specimens was assessed after delivering a dose of 12 Gy. PA changes at the beginning of a course of irradiation were compared with a degree of a radiation injury of tumor tissue after a course of irradiation was discontinued in 32 (explorative laparotomy was performed in 30). It was shown that tumor radioresistance could be predicted in unchanged PA indices of their increase at the beginning of a course of irradiation with the probability of 95%.

Published
1991

5. [A rare case of breast metastasis from thyroid cancer in a man].

Author

Belous TA and Efimova OIu

Subjects
Breast Neoplasms pathology, Humans, Male, Middle Aged, Neoplasms, Multiple Primary pathology, Adenocarcinoma pathology, Adenoma pathology, Breast Neoplasms secondary, Thyroid Neoplasms pathology
Published
1983

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