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Your search keyword '"Alfiler, Lauren"' showing total 2 results
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2 results on '"Alfiler, Lauren"'

1. Local connectivity and synaptic dynamics in mouse and human neocortex.

Author

Campagnola, Luke, Seeman, Stephanie C., Chartrand, Thomas, Kim, Lisa, Hoggarth, Alex, Gamlin, Clare, Ito, Shinya, Trinh, Jessica, Davoudian, Pasha, Radaelli, Cristina, Kim, Mean-Hwan, Hage, Travis, Braun, Thomas, Alfiler, Lauren, Andrade, Julia, Bohn, Phillip, Dalley, Rachel, Henry, Alex, Kebede, Sara, and Mukora, Alice

Subjects
*INTERNEURONS, *NEOCORTEX, *MICE, *NEURAL circuitry, *PYRAMIDAL neurons, *ACTION potentials
Abstract

The article presents an extensive and open synaptic physiology analysis platform and dataset. It reveals principles that relate cell type to synaptic properties and intralaminar circuit organization in the mouse and human cortex. Synaptic properties are heterogeneous in most subclass-to-subclass connections. In the human cortex, excitatory-to-excitatory synaptic dynamics are distinct from those in the mouse cortex and vary with depth across layers 2.

Published
2022
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2. Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex.

Author

Chartrand, Thomas, Dalley, Rachel, Close, Jennie, Goriounova, Natalia A., Lee, Brian R., Mann, Rusty, Miller, Jeremy A., Molnar, Gabor, Mukora, Alice, Alfiler, Lauren, Baker, Katherine, Bakken, Trygve E., Berg, Jim, Bertagnolli, Darren, Braun, Thomas, Brouner, Krissy, Casper, Tamara, Csajbok, Eva Adrienn, Dee, Nick, and Egdorf, Tom

Subjects
*INTERNEURONS, *NEOCORTEX, *TRANSCRIPTOMES, *MICE, *ACTION potentials, *PYRAMIDAL neurons
Abstract

The article discusses a study on the morphoelectric and transcriptomic differences between the layer 1 interneuron repertoire in the human and mouse neocortex. The study, conducted by Thomas Chartrand, Rachel Dalley, and their team, and published in the journal "Nature Neuroscience," reveals distinctions in the abundance of layer 1 cell types between humans and mice, along with differences in gene expression.

Published
2023
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