This volume provides a critical and comprehensive assessment of the relationship between gender, inequality and vulnerability to HIV infection and AIDS. It brings together contributions from scholars and practitioners from across the world to explore the relevance of these core concepts to their understanding of the AIDS crisis and the politics of effective response. The chapters in Gender and HIV/AIDS examine current thinking about sexuality, masculinity, gender roles, and culture in relation to HIV/AIDS and global politics of intervention and regulation. In doing so, the volume maps the intellectual and empirical dimensions of a global debate concerning the gendered contours of an epidemic imbedded in the social relations and material realities of societies at large. The normative aspiration of the volume is to stress the enormity and complexity of the relationship between gender inequalities, sexuality and HIV and AIDS, and the impact this has on the lives of affected and infected people, as well as on our work as development practitioners, academics, and activists. We believe that taking gender into account in our response to HIV/AIDS will not only help our understanding of the character and persistence of the epidemic, but has the potential of contributing to both improved policy and to the genuine transformation of gender relations in wider society. The epidemiological statistics show that today women are more vulnerable to HIV than men for a variety of biological and social reasons that will be discussed in this introduction and throughout the book. Policy-makers have recognized this phenomenon as the “feminization of AIDS” (CHGA n.d.; Global Coalition on Women and AIDS 2004; Germain and Kidwell 2005; Piot 2007). This awareness of women’s vulnerability has stepped up prevention work with women, and focused attention on HIV and gender. While this is a necessary development, it is not without controversy. Arguably, the focus on women reinforces patterns of stigma and blame directed at women, portraying them as either vectors or victims of the epidemic (AWID and Kinoti 2008; Busza, this volume). This is partly the result of how “gender” is often addressed in development policy, practice and scholarship, equating gender all too often with women. As a result of the tremendous difficulty of changing entrenched social relationships, policy rarely looks beyond “women’s inclusion,” overlooking the beliefs, norms and values that underpin inequality in