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Start Over Author "Schoene, K." Topic acetylcholinesterase
10 results on '"Schoene, K."'

3. [Reactivation of phosphorylated acetylcholinesterase. Isomeric bisquaternary salts of pyridine aldoximes].

Author

Hagedorn I, Stark I, Schoene K, and Schenkel H

Subjects
Chemical Phenomena, Chemistry, Isomerism, Pralidoxime Compounds chemical synthesis, Acetylcholinesterase metabolism, Enzyme Reactivators chemical synthesis, Pralidoxime Compounds pharmacology
Abstract

Mono-quaternary salts Z have been prepared from pyridine-aldoximes and 1,3-dihalogen compounds. These were used to synthesize asymmetrical bis-quaternary pyridine-oximes with three-membered bridge. The effect of reactivation of phosphorylated AChE by these substances is less than that of obidoxim (Toxogonin).

Published
1978

5. [Reactivation of diethylphosphoryl-acetylcholinesterase. Affinity and reactivity of some pyridinium oximes].

Author

Schoene K and Strake EM

Subjects
Amides, Chemical Phenomena, Chemistry, Chromatography, Thin Layer, Enzyme Activation, Ethers, Glycols, Infrared Rays, Isonicotinic Acids, Kinetics, Mathematics, Niacinamide, Nitrophenols, Organophosphorus Compounds, Phosphoric Acids, Potentiometry, Pralidoxime Compounds, Protein Binding, Spectrophotometry, Acetylcholinesterase, Oximes chemical synthesis, Pyridinium Compounds chemical synthesis
Published
1971
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