Search

Your search keyword '"Diego Ivan Caviedes Rubio"' showing total 5 results
Start Over Author "Diego Ivan Caviedes Rubio" Topic acetonitrile
5 results on '"Diego Ivan Caviedes Rubio"'

1. Thermodynamic analysis and preferential solvation of sulfanilamide in different cosolvent mixtures

Author

Rossember E. Cardenas-Torres, Sebastian de Jesus Polania-Orozco, Diego Ivan Caviedes-Rubio, Daniel Ricardo Delgado, and Claudia Patricia Ortiz

Subjects
Ethanol, Chemistry, Inorganic chemistry, Solvation, Sulfanilamide, Condensed Matter Physics, Electronic, Optical and Magnetic Materials, chemistry.chemical_compound, Materials Chemistry, medicine, Physical and Theoretical Chemistry, Solubility, Acetonitrile, medicine.drug
Abstract

The thermodynamic analysis and preferential solvation of the solubility of sulphanilamide (SA) in five cosolvent mixtures (ethanol + water; 1,4-dioxane + water, acetonitrile + water, dimethyl-sulph...

Published
2021
Full Text
View/download PDF

2. Temperature and cosolvent composition effects in the solubility of methylparaben in acetonitrile + water mixtures

Author

Nestor Enrique Cerquera, Daniel Ricardo Delgado, Alba Miledy Romero-Nieto, Jesús Polania-Orozco, and Diego Ivan Caviedes-Rubio

Subjects
010304 chemical physics, Methylparaben, Inorganic chemistry, 02 engineering and technology, Condensed Matter Physics, 01 natural sciences, Electronic, Optical and Magnetic Materials, chemistry.chemical_compound, 020401 chemical engineering, chemistry, 0103 physical sciences, Materials Chemistry, Composition (visual arts), 0204 chemical engineering, Physical and Theoretical Chemistry, Solubility, Acetonitrile
Abstract

The solubility of methylparaben was determined in acetonitrile + water mixtures at several temperatures (278.15 K to 318.15 K). The solubility curves as a function of acetonitrile ratio showed a ma...

Published
2019
Full Text
View/download PDF

3. Solubility of sulphadiazine in (acetonitrile + water) mixtures: measurement, correlation, thermodynamics and preferential solvation

Author

Fleming Martínez, William E. Acree, Seyyedeh Narjes Mirheydari, Abolghasem Jouyban, Diego Ivan Caviedes-Rubio, María Á. Peña, Claudia Patricia Ortiz, Daniel Ricardo Delgado, and Yarly Lizeth Parra-Pava

Subjects
010304 chemical physics, Solvation, Thermodynamics, 02 engineering and technology, Condensed Matter Physics, 01 natural sciences, Electronic, Optical and Magnetic Materials, chemistry.chemical_compound, 020401 chemical engineering, chemistry, 0103 physical sciences, Materials Chemistry, 0204 chemical engineering, Physical and Theoretical Chemistry, Solubility, Acetonitrile, Dissolution
Abstract

The equilibrium solubility at temperatures from (293.15 to 313.15) K, dissolution thermodynamics and preferential solvation of sulphadiazine (SD) in {acetonitrile (ACN) (1) + water (2)} mixtures is...

Published
2019
Full Text
View/download PDF

4. Thermodynamic analysis and preferential solvation of sulfamethazine in acetonitrile + water cosolvent mixtures

Author

Claudia Patricia Ortiz, Nestor Enrique Cerquera, Joaquín H. Blanco-Márquez, Fleming Martínez, Daniel Ricardo Delgado, and Diego Ivan Caviedes Rubio

Subjects
010405 organic chemistry, Chemistry, General Chemical Engineering, Solvation, General Physics and Astronomy, Thermodynamics, Inverse, 02 engineering and technology, 01 natural sciences, Endothermic process, 0104 chemical sciences, chemistry.chemical_compound, 020401 chemical engineering, Molecule, 0204 chemical engineering, Physical and Theoretical Chemistry, Solubility, Acetonitrile, Solution process, Mixing (physics)
Abstract

This paper presents the solubility of sulfamethazine (SMT) in the acetonitrile (MeCN) + water (W) cosolvent system at nine temperatures. From the solubility experimental data, the thermodynamic functions of solution, mixing, and transfers are calculated and analyzed using the Perlovich graphical method. On the other hand, an enthalpy−entropy compensation analysis is performed and the preferential solvation parameters are calculated using the Kirkwood-Buff (IKBI) inverse integral method. The result of the performed calculations indicates that the SMT solution process is endothermic with entropic favor, where the addition of MeCN has a positive cosolvent effect between pure water and the mixture with w1 = 0.90. As for the preferential solvation, the SMT molecule is preferentially surrounded by water in water- and MeCN-rich mixtures, and in intermediate mixtures, the SMT molecule tends to be surrounded by MeCN.

Published
2020
Full Text
View/download PDF

5. Dissolution Thermodynamics of the Solubility of Sulfamethazine in (Acetonitrile + 1-Propanol) Mixtures

Author

Daniel Ricardo Delgado, Jennifer Katiusca Castro-Camacho, Claudia Patricia Ortiz, Diego Ivan Caviedes-Rubio, and Fleming Martinez

Subjects
sulfamethazine, solubility, acetonitrile, 1-propanol, cosolvency, solution thermodynamics, Medicine, Pharmacy and materia medica, RS1-441
Abstract

Background: Solubility is one of the most important parameters in the research and development processes of the pharmaceutical industry. In this context, cosolubility is one of the most used strategies to improve the solubility of poorly soluble drugs, besides allowing to identify some factors involved in the dissolution process. The aim of this research is to evaluate the solubility of sulfamethazine in acetotinitrile + 1-propanol cosolvent mixtures at 9 temperatures (278.15, 283.15, 288.15, 293.15, 298.15, 303.15, 308.15, 313.15, and 318.15 K); a drug used in human and veterinary therapy and two solvents of great chemical–pharmaceutical interest. Methods: The determination was carried out by the shaking flask method and the drug was quantified by UV/Vis spectrophotometry. Results: The solubility of sulfamethazine increases from pure 1-propanol (solvent in which it reaches its lowest solubility at 278.15 K) to pure acetonitrile (solvent in which it reaches its maximum solubility at 318.15 K), behaving in a logarithmic-linear fashion. Conclusions: The increase in solubility is related to the acid/base character of the cosolvent mixtures and not to the solubility parameter of the mixtures. The dissolution process is endothermic and favored by the solution entropy, and also shows a strong entropic compensation.

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results