1. [Prescription of acetaminophen in five French hospitals: What are the practices?]
- Author
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Pace JB, Nave V, Moulis M, Bourdelin M, Coursier S, Jean-Bart É, Leroy B, Bonnefous JL, Bontemps H, Coutet J, Eyssette C, and Pont E
- Subjects
- Aged, Aged, 80 and over, Drug Misuse statistics & numerical data, Female, Hospitals statistics & numerical data, Humans, Male, Prospective Studies, Acetaminophen therapeutic use, Analgesics, Non-Narcotic therapeutic use, Drug Prescriptions statistics & numerical data
- Abstract
Aim: Acetaminophen is widely used in hospital settings and often considered as nontoxic. We conducted a multicentric study in order to evaluate its proper use., Method: Prescriptions from five general hospitals were analyzed, according to dose adjustments required in renal or liver failure, weight or chronic alcoholism, determined using a literature review. Other criteria have been assessed: indication for parenteral access, accuracy of administration time and pain assessment., Results: Among the 1256 analyzed prescriptions, 21% are non-compliants. The main causes of non-compliance (NC) are adjustments to weight and renal failure. Higher NC rates concern chronic alcoholism and liver failure., Conclusion: Misuse of acetaminophen seems related to a lack of official recommendations concerning dose adjustments. Hospital pharmacists have an important role to play in the promotion of proper use of acetaminophen. Therefore we established a prescribing aid., (Copyright © 2017 Société française de pharmacologie et de thérapeutique. Published by Elsevier Masson SAS. All rights reserved.)
- Published
- 2017
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