Plants are the great sources of medicines, especially in traditional system of medicine, which are useful in the treatment of various diseases. Blepharis molluginifolia Pers. is threatened medicinal herb belongs to the family Acanthaceae. The plant selected for the present study is used traditionally to treat bone fractures, skin diseases, urinary discharges, and allergies. Further, it has not yet been studied pharmacognostically. Hence, the present study is aimed to know the pharmacognostic parameters to determine the quality of the plant Blepharis molluginifolia. This study comprises the detailed macroscopic, microscopic and preliminary phytochemical investigations of the herb were studied. [ABSTRACT FROM AUTHOR]