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Start Over Author "Richter SA" Topic aac(6')-ib-cr
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1. Prevalence of aac(6')-Ib-cr plasmid-mediated and chromosome-encoded fluoroquinolone resistance in Enterobacteriaceae in Italy

Author

Frasson Ilaria, Cavallaro Antonietta, Bergo Cristina, Richter Sara N, and Palù Giorgio

Subjects
aac(6')-Ib-cr, fluoroquinolones, plasmid-mediated resistance, Gram-negative, Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Abstract The spread of aac(6')-Ib-cr plasmid-mediated quinolone resistance determinants was evaluated in 197 enterobacterial isolates recovered in an Italian teaching hospital. The aac(6')-Ib-cr gene was found exclusively in Escherichia coli strains. The gene was located on a plasmid which presented additional ESBL genes. Most of the clinical strains were clonally related and displayed three point mutations at the topoisomerase level which conferred high resistance to fluoroquinolones.

Published
2011
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